目的 研究武警某执勤部队战士膳食铁与血脂间的关系,为进一步提供合理膳食结构、保持机体血脂代谢平衡提供理论基础。方法 115名战士作为调查对象,采用3 d称重法对其食堂伙食供应情况连续调查,计算其食物总铁元素、动物来源的血红素铁及植物来源的非血红素铁摄入量;取空腹静脉血,全自动生化分析仪检测血浆总胆固醇(total cholesterol,TC)、三酰甘油(triglycerides,TG)、高密度脂蛋白胆固醇(HDL cholesterol,HDL-C)和低密度脂蛋白胆固醇(LDL cholesterol,LDL-C),采用多元回归分析食物总铁元素、动物性食物来源的血红蛋白铁,以及植物性食物来源的非血红蛋白铁摄入量与血脂之间关联;单因素方差分析不同区间食物总铁元素、动物来源的血红蛋白铁,以及植物来源的非血红蛋白铁等不同铁摄入量其血脂异常发病率的差异。结果 每日膳食中总铁、动物性食物来源的血红蛋白铁以及植物性食物来源的非血红蛋白铁摄入量的平均值分别为47.1、26.5、19.9 mg,食物总铁和动物源性铁含量与血浆总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)呈正相关(P＜0.05)。随着不同区间食物总铁和动物源性铁摄入量中位数的增加,血脂异常的发病率逐渐增加。结论 动物源性膳食铁可显著影响血脂水平。
Abstract
Objective To investigate the associations between intake of the dietary iron and blood lipid in the soldiers of Armed Police Forces. Methods Dietary survey for 3 days by dietary weighing method was made and the total iron content, heme-iron and non heme-iron intakes were counted in 115 soldiers. Fasting total cholesterol (TC), triglycerides (TG), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) were also measured. Logistic regression models and one-way ANOVA were used to assess associations and prevalence between the total iron content, heme-iron and non heme-iron intakes and dyslipidemia risks after adjusting for age, BMI and energy consumption. Results The average iron intake was higher than the Chinese DRIs value. The total dietary iron, heme iron and non-heme iron contents were 47.1mg, 26.5mg and 19.9mg, respectively. The total dietary iron content and heme-iron were positively associated with the blood total cholesterol (TC), triglycerides (TG), and low density lipoprotein cholesterol (LDL-C) (P＜0.05). With increasing dietary iron content and heme-iron, dyslipidemia risks were significantly increased.Conclusion Dietary iron from animal foods may have a bad effect on the blood lipid levels.
关键词
武警 /
膳食铁 /
血脂异常
Key words
Armed Police Forces /
dietary iron /
blood lipid
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Habib A, Finn A V. The role of iron metabolism as a mediator of macrophage inflammation and lipid handling in atherosclerosis [J]. Front Pharmacol,2014,27,5:195.
[2] Simcox J A,Mitchell T C,Gao Y,et al. Dietary iron controls circadian hepatic glucose metabolism through heme synthesis [J]. Diabetes,2015,64(4):1108-1119.
[3] Fang X,An P,Wang H,et al. Dietary intake of heme iron and risk of cardiovascular disease: a dose-responsemeta-analysis of prospective cohort studies [J]. Nutr Metab Cardiovasc Dis,2015,25(1):24-35.
[4] Pasquale L R,Loomis S J,Aschard H,et al. Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes [J]. Front Genet,2013,30(4):7.
[5] Krishnan C, Washabaugh E P, Seetharaman Y. A low cost real-time motion tracking approach using webcam technology [J]. J Biomech,2015,48(3):544-548.
[6] Yuexin Y, Guangya W, Xingchang P. China Food Composition 2004[M]. Beijing: Peking University Medical Press.
[7] Hu D Y,Ding R J. Guidelines for management of adult dyslipidemia in China [J]. Zhonghua Nei Ke Za Zhi,2008,47(9):723-724.
[8] Gulec S,Anderson G J,Collins J F. Mechanistic and regulatory aspects of intestinal iron absorption [J]. Am J Physiol Gastrointest Liver Physiol,2014,307(4):G397-409.
[9] Ley S H,Hamdy O,Mohan V,et al. Prevention and management of type 2 diabetes: dietary components and nutritional strategies [J]. Lancet,2014,383(9933):1999-2007.
[10] Gudjoncik A,Guenancia C,Zeller M,et al. Iron,oxidative stress,and redox signaling in the cardiovascular system [J]. Mol Nutr Food Res,2014,58(8):1721-1738.
PDF(550 KB)
