目的 探讨高原施工人员不同海拔高度、不同居住时间氧疗前后微循环的变化。方法 选取2000名高原施工人员,在不同海拔,监测并分析3、7、15、30、60、90 d、1年吸氧前后微循环变化。结果 吸氧组微循环血流、血管形态、红细胞聚集、管襻形态、襻顶淤血、襻周出血、乳头下血管丛等变化明显优于不吸氧组 。吸氧前血液流态积分显著降低,前后比较差异有统计学意义(χ²=6.48,P<0.05),管周状态差异有统计学意义(χ²=4.36,P<0.05),积分显著增高,差异有统计学意义(P<0.05),海拔5 000 m以上吸氧后较吸氧前管周状态积分增高非常显著(P<0.01)。其他积分和总积分虽有增高或降低,均无统计学意义。结论 微循环变化明显好于对照组,尤其是血管清晰度、血液流态流速、血管变异、红细胞聚集等方面。

Objective To study the change of microcirculation in construction personnel residing on different altitude and for different time before and after oxygen therapy.Methods Microcirculation changes in 2 000 plateau construction personnel in different altitude, 3, 7, 15, 30, 60, 90 d, 1 y before and after oxygen therapy were observed. Results In oxygen groups, microcirculation blood flow, blood vessels, erythrocyte aggregation, tube loop, loop congestion, loop bleeding, vascular plexus under nipple, were better than in no oxygen groups. blood flow integral was significantly reduced before oxygen, comparison before and after was sigmticantlg different (χ²=6.48, P<0.05), comparison of pipe weeks state both showed significant difference (χ²=4.36, P<0.05), scores were significantly higher (P<0.05) at an altitude of more than 5 000, oxygen status before the oxygen tube weeks after integral increased significantly (P<0.01). Other integral and total integral was higher or lower, without statistically significant difference. Conclusions Microcirculation changes are much better than those in groups without oxygen, especially the clarity of blood vessels, the blood flow velocity variation, erythrocyte aggregation, blood vessels, etc.