目的 应用定位CT与食管X线钡剂造影结合的方法测量食管癌病变长度,为快速、准确勾画食管癌GTV长度提供依据。方法 60例初治食管鳞癌患者拟行根治性放射治疗,在模拟定位机下吞钡行X线钡剂造影,用铅珠标记,确认食管癌病变两端长度,在相同体位固定下CT扫描。采用One-Way ANOVA方差分析进行统计分析。结果 食管癌病变长度从大到小依次为CT扫描长度、X线钡餐造影长度(铅珠标记)和内镜长度,三种检测方法分别为(8.82±2.40)cm、(7.03±1.74)cm和(6.27±1.68)cm,差异有统计学意义(P<0.05)。结论 应用定位CT与X线钡剂造影结合的方法,参考内镜检查结果,在CT上能够快速确定食管癌GTV长度。
Abstract
Objective To provide the proof for the fast, accurate delineation of esophageal carcinoma GTV length by measuring the GTV-T length differences detected by CT and barium meal. Methods 60 patients with esophageal squamous cell carcinoma undergoing radical radiation therapy, swallowed barium and took a fluoroscopy;while the upper and lower bounds of lesions determined,which were marked and fixed on the skin. The same posture was located according to the CT simulation.One-Way ANOVA analysis of variance was used for statistical analysis.Results The length of esophageal carcinoma from high to low in order for the CT scan length, X-ray and endoscope length,there was significant difference in GTV-T length among the three methods(P<0.05).Conclusions Referring to esophagoscopic results, the GTV length of esophageal carcinoma can be quickly determined by CT and barium meal.
关键词
食管肿瘤 /
三维适形放疗 /
食管钡餐造影 /
靶区 /
长度
Key words
esophageal neoplasm /
three-dimensional conformal radiotherapy /
esophagogram /
target /
tumor length
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参考文献
[1] Minsky B D, Pajak T F, Ginsberg RJ,et al.INT 0123 (Radiation Therapy Oncology Group 94-05) phase III trial of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy[J]. J Clin Oncol,2002, 20(5):1167-1174.
[2] Dai T, Shah MA.Chemoradiation in oesophageal cancer[J]. Best Pract Res Clin Gastroenterol,2015,29(1):193-209.
[3] 陈俊强,潘建基,陈明强,等.应用CT画胸段食管癌肿瘤靶区准确性研究[J].中华放射肿瘤学杂志, 2008, 17(2):90-92.
[4] Drudi F M, Trippa F, Cascone F,et al. Esophagogram and CT vs endoscopic and surgical specimens in the diagnosis of esophageal carcinoma[J]. Radiol Med,2002,103(4):344-352.
[5] 中国非手术治疗食管癌临床分期专家小组.非手术治疗食管癌的临床分期标准(草案)[J].中华放射肿瘤学杂志, 2010,19(3):179-180.
[6] 黄拔群,刘耿淳,李 青,等.应用CT结合钡餐造影确定食管癌靶区长度的研究[J].现代肿瘤医学, 2013, 21(11):2587-2589.
[7] 营巧玲,李前文,杜云翔.非手术食管癌个体化放疗的靶区勾画进展[J].临床肿瘤学杂志, 2014,19(10):940-944.
[8] 王 军,祝淑钗,韩 春,等.CT 扫描食管造影和内窥镜测量食管癌病变长度的价值[J]. 中国肿瘤临床,2008,35(17):967-970.
[9] 王 军,韩 春,祝淑钗,等.基于食管癌病理标本长度推算的实际长度与CT长度的比较研究[J].中华放射肿瘤学杂志, 2008,17(2):93-96.