目的 比较功能性烧心(functional heartburn,FH)和难治性胃食管反流病(refractory gastroesophageal reflux disease,rGERD)的临床特征。方法 对24小时Ph-阻抗监测确定的8例FH和38例rGERD患者的临床资料进行分析。问卷包括一般情况、胃食管反流病、反流症状积分表(RSS),以及焦虑(SAS)、抑郁(SDS)评价量表等。结果 FH和rGERD患者的性别、年龄、体质指数(BMI)、典型症状、吸烟饮酒史、RSS、SAS、SDS评分间的差异无统计学意义;但rGERD患者胃食管反流病问卷(GerdQ)得分(中位数8)显著高于FH组(中位数6),差异有统计学意义(P＜0.01)。结论 FH患者的GerdQ 评分明显低于rGERD患者。

Objective To compare the difference in clinical epidemiologic features between patients with functional heartburn and patients with refractory gastroesophageal reflux disease (rGERD). Methods The clinical data of eight patients with functional heartburn and 38 patients with rGERD identified by 24-hour impedance/pH monitoring were analyzed retrospectively. The questionnaire including demography characteristics and GERD questionnaire (GerdQ), reflux symptoms scale (RSS) along with Self-rating Anxiety scale (SAS) and Self-rating Depression Scale(SDS) were used. All the data were input into database by using EpiData 3.0 software and analyzed using SPSS 15.0 software. Results There were no significant differences in the age, gender, body mass index (BMI, kg/m²), symptoms as well as scores of RSS, SAS and SDS (P>0.05) between the two groups. However, GerdQ score in patients with rGERD group (median 8) was higher than FH group (median 6)(P<0.01). Conclusions GerdQ score in FH group is significantly lower than that in rGERD group.