目的 应用冠状动脉CT血管成像技术(computed tomography angiography,CTA)确定有高危因素,且非糖尿病无冠心病症状者冠状动脉粥样硬化(coronary atherosclerotic, CA)发生率,评价其与高危因素的相关性。方法 在非糖尿病无冠心病症状健康查体的人群中,收集有高危因素(性别、年龄、高血压、高脂血症)者并将其分为单项高危因素组、2项及以上高危因素组。统计有高危因素者冠状动脉粥样硬化发生率。结果 单因素分析发现,年龄和性别对CA的发生率有统计学差异(χ2 ＝4.6,P＝0.0032,χ2＝6.5,P＝0.0108)。高危因素logistic回归分析得出,年龄与CA的发生率有相关性(OR＝1.77,CI＝1.19～2.66)。高危因素组间比较,多项高危因素CA的发生率有统计学差异(χ2＝4.44,P=0.035)。结论 在非糖尿病无症状人群中,CTA能够在一次扫描提供冠状动脉斑块的重要信息,性别、年龄可能对发生CA病变带来更大的风险,作为一项无创性的检查,CTA在CA的诊断中发挥重要作用。
Abstract
Objective To make use of coronary CTA to determine the incidence rate of coronary atherosclerosis for non-diabetic asymptomatic people who have risk factors and evaluate its correlation with risk factors. Methods We recruited non-diabetic asymptomatic people who had high-risk factors (sex, age, hypertension, hyperlipidaemia) and divided them into single high-risk factor group and multiple high-risk factors group. Statistics was conducted on the incidence rate of disease for people who had high-risk factors in coronary atherosclerosis. Results Single risk factor grouping analysis showed that gender and age had significant difference in the incidence of CA(χ2＝4.6,P＝0.0032,χ2＝6.5,P＝0.0108) . For risk factors between groups, the incidence of multiple risk factors CA had significant difference (χ2＝4.6,P＝0.0032,χ2＝6.5,P＝0.0108). Logistic regression analysis showed that risk factors correlated with age and incidence of CA (OR＝1.77, CI＝1.19-2.66). Conclusions In asymptomatic non-diabetic population, CTA provides important information about coronary plaque in one scan, gender and age may have a greater risk of CA disease. As a non - invasive examination, CTA plays an important role in the diagnosis of CA.
关键词
冠状动脉粥样硬化 /
CT血管成像 /
危险因素
Key words
coronary atherosclerosis /
CTA /
risk factors
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