目的 分析切除中枢神经细胞瘤(central neurocytoma,CNC)的两种不同术式的手术效果及术后并发症。方法 回顾性分析2012-09至2014-08,北京天坛医院神经外科收治的CNC患者87例,按照手术切除肿瘤入路不同将其分为,经纵裂-胼胝体组(27例)和经皮层造瘘组(60例),对比分析两组患者的术前症状、切除率及术后并发症。结果 经纵裂-胼胝体组全切7例(25.9%),经皮层造瘘组全切18例(30.0%),两组相比差异无统计学差异。对比术后病发症,经纵裂-胼胝体组术后出现肌力下降发生率为3例(11.1%),癫痫发生率仅为1例(3.7%)。而经皮层造瘘组术后出现肌力下降发生率为9例(15.0 %),发生癫痫为9例(15.0%),两组比较差异有统计学意义(P<0.05)。结论 两种术式均为切除CNC的主要手术方法,但经纵裂-胼胝体组术后发生癫痫及肌力下降的明显低于经胼胝体入路切除肿瘤组。
Abstract
Objective To analyze the different surgical results of removing central neurocytomas by different operation methods, and discuss the postoperative complications. Methods 87 patients with central neurocytoma admitted to this hospital between September 2012 and August 2014 were enrolled and divided into two groups according to different surgical approaches. Group 1 (27 cases) underwent operation by interhemispheric transcallosal approach, while group 2 (60 cases) had their tumors removed through cortex colostomy. Preoperative symptoms, removal rate and postoperative complications in the two groups were retrospectively analyzed. Results The total removal rates were 26% (7 cases) and 30% (18 cases) in group 1 and group 2, respectively. In group 1, decline of muscle strength occurred in 3 cases (11.1%), and epilepsy in 1 case (3.7%); in group 2, decline of muscle strength and epilepsy both occurred in 9 cases (15.0%). Conclusions Both methods are primary treatment choice for central neurocytoma with good prognosis. But decline in muscle strength and epilepsy are more likely to occur when the tumors are removed through cortex colostomy than by interhemispheric transcrallosal approach.
关键词
中枢神经细胞瘤 /
手术入路 /
术后并发症
Key words
central neuroytoma /
surgical approach /
post-operative complications
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