目的 探讨高尿酸血症对Ⅱ型心肾综合征心功能的影响。方法 选择120例Ⅱ型心肾综合征患者,根据血尿酸水平,将其分为高尿酸组和正常尿酸组,检测并比较两组年龄、血压、胆固醇、血糖、血肌酐、尿蛋白、血浆NTproBNP、左室舒张末径。结果 120例Ⅱ型心肾综合征患者中发生高尿酸血症88例(73.3%)。高尿酸组与正常尿酸组的肾功能、血压、血糖、血脂比较无统计学意义;高尿酸组NTproBNP为(2483.7±296.5) pg/ml、左室舒张末径(53.2±6.9)mm,正常尿酸组NTproBNP(2203.5±176.7)pg/ml、左室舒张末径(52.9±4.8)mm,两组比较差异无统计学意义。结论 高尿酸血症在Ⅱ型心肾综合征患者中发生率高,但对心功能无影响。
Abstract
Objective To investigate the effecthyperuricemiaon patients’of cardiac function in cardiorenal syndrome type Ⅱ. Methods 120 patients with types Ⅱcardiorenal syndrome, according to their level of serum uric acid, were divided into hyperuricemia group and normal uric acid group, and the differencesin related indexes of cardiac function were analyzed. Results Of 120 patients with type Ⅱcardiorenal syndrome, 88(73.3%) had hyperuricemia. Betweenhigh uric acid group and normal uric acid group, renal function, blood pressure, blood glucose, and blood lipid showed no statistically significant difference (P>0.05), NTproBNP in high uric acid group was (2483.7±296.5) pg/ml, left ventricular end diastolic diameter was (53.2±6.9) mm, while those in normal uric acid group were (2203.5±176.7) pg/ml and (52.9±4.8)mm,respectively the difference showed no statistical significance. Conclusions Hyperuricemia in patients with cardiorenal syndrome type Ⅱ is in highly incident, but has no effects on their cardiac function.
关键词
Ⅱ型心肾综合征 /
高尿酸血症
Key words
cardiorenal syndrome type Ⅱ /
hyperuricemia
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参考文献
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