目的 分析泌尿系感染患者尿液中的病原菌分布特点及其耐药情况,以指导临床合理用药。方法 收集我院2013-01至2014-06泌尿系感染患者尿液标本中分离出的菌株共384株,回顾性分析所感染病原菌的分布特点及耐药情况。结果 384株泌尿系感染病原菌分布以革兰阴性杆菌为主,占65.63%,其中41.41%为大肠杆菌;革兰阳性球菌占23.44%,以肠球菌属为主;真菌占10.93%。大肠埃希菌ESBLs检出率为 71.7%。结论 泌尿系感染细菌的耐药性日趋严重,及时总结、分析,对于控制多重耐药菌株产生及传播,指导合理使用抗菌药物具有十分重要的意义。

Objective To analyze the distribution and drug resistance of common species of pathogens causing urinary tract infections so as to provide guidance for reasonable clinical choice and use of medicine. Methods The clinical data of the patients in this hospital from January 2013 to June 2014 were retrospectively investigated. The distribution and drug resistance of 384 strains of pathogens were analyzed. Results In the 384 strains of bacteria, 65.63% were Gram-negative, 23.44% were Gram-positive and 10.93% were fungi. Most of Gram-positive bacteria were E.coli and Enterococci were dominant among the Gram-positive bacteria. The detection rates of the extended-spectrum β-lactamases (ESBLs) producing E.coli were 71.7%. Conclusions The drug resistance of such pathogens is increasing year by year. It is of great significance to analyze the distribution and antibiotic resistance of isolated bacteria in urinary tract infection to control resistant strains.