目的 探讨临产妇预防性使用间苯三酚的临床价值:是否可以减少宫颈水肿的发生，是否可以缩短第一产程等等。方法 选择武警总医院2014-02至2014-11孕足月、单胎、头位初孕妇共100例作为试验组，试验组在出现规律宫缩后，即给予间苯三酚80 mg静推1次/2 h，鉴于间苯三酚日最大剂量的影响，每天最多推2次。同期选择100例孕妇作为对照组。对照组未给予任何处置，任其产程自然进展。比较两组第一产程、第二产程、第三产程时间，宫颈水肿的发生人数，中转剖宫产人数，产后2 h出血量，新生儿Apgar评分。结果 试验组第一产程较对照组明显缩短，差异有统计学意义(P<0.05)。第二产程、第三产程差异无统计学意义。试验组宫颈水肿4例，对照组16例，差异有统计学意义(P<0.05)。试验组、对照组分别有16例和29例产妇试产失败后转为剖宫产，两组比较差异有统计学意义(P<0.05)。产后2 h出血量，新生儿Apgar评分两组比较无显著差异。结论 间苯三酚为安全解痉药物，可早期预防性应用。本研究证实，临产妇预防性使用间苯三酚可以有效降低宫颈水肿的发生率，缩短第一产程，降低剖宫产率，且对母儿无不良影响。

Objective To study the clinical value of prophylactic use of phloroglucinol in the incubation period. Methods From February 2014 to November 2014, a total of 100 full-term pregnant, monocyesis and primigravid women were recruited as study group, after regular contractions developed, they were given phloroglucinol 80 mg intravenously every 2 hours, twice a day at most . At the same time another 100 pregnant women were recruited as control group; they did not receive any disposal and et the labor naturally progress. Between two groups, the first, second and third stages of labor time, number of patients with cervix edema, transter number of cesarean section, 2 h bleeding roluml after delivery, neonatal Apgar score were compared. Results The first stage of labor in the study group was shortened obviously, the difference was statistically significant (P<0.05).The second and third stages of labor had no statistically significant difference (P<0.05).the cervix edema developed in 4 cases in the study group , 16 cases in the control group, the difference was statistically significant. In the study group and control group, 16 cases and 29 cases failed and turned to cesarean section; the difference was significant between the two groups (P<0.05). 2 h postpartum blood loss and neonatal Apgar score between the two groups were to significantly different. Conclusion Phloroglucinol as a safe spasmolytic medicine, also can be applied to the early clinical stage for prevention.This study confirmed that preventive use of phloroglucinol in the incubation period can effectively reduce the incidence rate of cervix edema, shorten the first stage of labor and reduce cesarean delivery rate; and has no adverse effect on mother and fetus.