目的 分析糠酸莫米松鼻喷雾剂联合通窍鼻炎颗粒治疗变应性鼻炎的疗效。方法 变应性鼻炎128例随机分为观察组(64例)与对照组(64例),观察组给予糠酸莫米松鼻喷雾剂+通窍鼻炎颗粒治疗,对照组单独用糠酸莫米松鼻喷雾剂治疗,对比分析两组症状、体征变化情况、不良反应发生情况及1年复发情况。结果 观察组总有效率为92.19%,对照组总有效率为70.31%,两组差异有统计学意义(P<0.05);两组治疗前临床症状、体征积分无统计学差异,治疗后,观察组临床症状、体征评分低于对照组,差异有统计学意义(P<0.05);两组均无严重药物不良反应发生,观察组1年复发率为14.06%,对照组1年复发率为17.19%。结论 糠酸莫米松鼻喷雾剂联合通窍鼻炎颗粒治疗变应性鼻炎的临床效果显著。

Objective To analyze the clinical effect of mometasone furoate nasal spray combined with Tongqiaobiyan granules in the treatment of allergic rhinitis. Methods 128 patients with allergic rhinitis from June 2012 to June 2014 admitted to this hospital were randomly divided into the study group (64 cases) and the control group (64 cases). The study group received mometasone furoate nasal spray + Tongqiaobiyan granules;the control group was treated with mometasone furoate nasal spray alone. Comparative analysis of symptoms and signs of change, adverse reaction and 1-year recurrence was conducted between the two groups of patients. Results The total effective rates were 92.19% in the study group, and 70.31% in the control group (P<0.05). The clinical symptoms and signs in the two groups before treatment were not significantly different (P>0.05). The clinical symptoms and signs of the two groups after treatment were significantly different (P<0.05); the recurrence rate in the study group was after one year was 14.06%, and the recurrence rate in the control group after one year was 17.19%, and the difference was not significant. Conclusions The clinical efficacy of mometasone furoate nasal spray combined with tongqiaobiyan granule in the treatment of allergic rhinitis is encouraging.