目的 评价表观弥散系数(apparent diffusion coefficient,ADC)在不同组织来源的肝脏转移瘤的诊断价值。方法 回顾性分析45例经1.5T MRI检查的肝脏转移瘤患者的扩散加权图像,采用单因素方差分析276处肝脏转移瘤的ADC值,比较不同肿瘤组间的差异性。结果 来源于胃直肠癌、肝癌、乳腺癌的肝脏转移瘤的平均ADC值间的差异无统计学意义。来源于肺癌的肝脏转移瘤的平均ADC值低于其他来源的肝脏转移瘤,差异有统计学意义(P<0.05)。来源于胰腺癌的肝脏转移瘤的平均ADC值高于其他来源的肝脏转移瘤,差异有统计学意义(P<0.05)。结论 ADC值在肺癌和胰腺癌来源的肝脏转移瘤的诊断中有一定的价值。
Abstract
Objective To evaluate apparent diffusion coefficient values in the diagnosis of liver metastases from different primary tumors.Methods Diffusion-weighted imaging in 45 patients after 1.5T MRI examination was retrospectively analysized. The ADC values of 276 liver metastases were measured and performed with one-way ANOVA to compare the difference in different primary tumors.Results No significant difference in ADC values were found between gastrointestinal malignant tumor, liver cancer and breast cancer (P>0.05).The ADC mean values in lung cancer were lower than in other primary tumors with statistically significant difference (P<0.05). Those values in pancreatic carcinoma were significantly higher than in other primary tumors (P<0.05).Conclusions The ADC values are helpful to diagnosis of liver metastases from lung cancer and pancreatic carcinoma.
关键词
肝脏 /
转移瘤 /
扩散加权成像 /
表观弥散系数
Key words
Liver /
Metastases /
Diffusion-weighted imaging /
Apparent diffusion coefficient
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Bachir Taouli, Dow-Mu Koh. Diffusion-weighted MR imaging of the liver [J]. Radiology, 2010, 254(1):47-66.
[2] Surov A, Ryl I, Bartel-Friedrich S, et al. Diffusion weighted imaging of nasopharyngeal adenoid hypertrophy[J]. Acta Radiol, 2015, 56(5):587-591.
[3] 王 叶,吴南洲,王 佳,等.扩散加权成像在鉴别肝脏转移瘤和肝内胆管细胞癌中的价值[J].中国临床医学影像杂志,2013,21(3):214-217.
[4] 张海兵,钟 喨. ADC值在鉴别肝脏良恶性局灶性病变的应用价值[J].医学影像学杂志,2013,23(7):1044-1048.
[5] Nagihan I, Furkan K, Tahsin S, et al. Diffusion weighted MR imaging in the differential diagnosis of haemangiomas and metastases of the liver[J]. Radiol Oncol, 2010,44(1): 24-29.
[6] Muhi A, Ichikawa T, Motosugi U, et al. High-b-value diffusion-weighted MR imaging of hepatocellular lesions:estimation of grade of malignancy of hepatocellular carcinoma[J]. J Magn Reson Imaging,2009,30(5):1005-1011.
[7] 李 菲,于铁链,李伟栋,等. ADC值与肺癌组织学类型及分化程度的相关性研究[J].中国肺癌杂志,2012,15(11):646-651.
[8] Koh D M, Collins D J. Diffusion-weighted MRI in the body: applications and challenges in oncology[J]. AJR,2007,188(6):1622-1635.
[9] Meyer H J, Fiedler E, Kornhuber M, et al. Comparison of diffusion-weighted imaging findings in brain metastases of different origin[J]. Clin Imaging,2015,39(6):965-969.
[10] 许丽萍,郑海燕,孙翠云. 210例肺癌患者临床病理特征回顾性分析[J].黑龙江医学,2015,39(6):646-647.
[11] 李忠明,陈自谦,钟 群,等. 3.0TMRI对胰腺导管腺癌的诊断价值及与病理对照[J].中国CT和MRI杂志,2013,11(4):62-66.
[12] 陈 杰.胰腺肿瘤的病理诊断和鉴别诊断[J].临床肝胆病杂志,2013,29(1):45-49.
PDF(1033 KB)
