目的 观察体外冲击波治疗中老年女性膝关节炎的疗效。方法 将2014-08至2014-12收集到的65例女性膝关节炎患者随机分为两组,氨糖组给予硫酸氨基葡萄糖胶囊口服, 1～2粒(0.314～0.628 g)/次,连续服用8周。冲击波组给予冲击频率为7 Hz,能量1～2 bar的发散式体外冲击波治疗,每个部位冲击2000下,1次/周,8次为一疗程。对两组患者治疗前及治疗一疗程后行视觉模拟疼痛评分(visual analog scale,VAS),膝关节功能评分(Western Ontario and McMaster University Osteoarthritis Index,WOMAC)及测量50 m快速走时间。结果 两组患者均未见严重不良反应,体外冲击波组患者疼痛缓解,平均VAS疼痛评分(3.2±2.4)较治疗前(6.8±2.2)明显下降,差异有统计学意义(P<0.05)。膝关节功能WOMAC指数均较治疗前有改善(P<0.05)。 50 m快速走平均时间(37.0±6.3)s较治疗前(39.9±7.7)s明显缩短,差异有统计学意义(P<0.05)。对照组VAS疼痛评分,膝关节功能WOMAC指数,50 m快速走时间变化无明显统计学意义。结论 相对于口服氨基葡萄糖,体外冲击波疗法治疗中老年女性膝骨关节炎无不良反应,能缓解疼痛,恢复关节功能,可作为治疗骨关节炎的新选择。
Abstract
Objective To study the effect of extracorporeal shock wave therapy on middle-aged and old women with knee osteoarthritis.Methods We recuited patients from August 2014 to December 2014. 65 female patients with knee arthritis were randomly divided into two groups: Glucosamine ammonia sugar group was given glucosamine sulfate capsules orally, 1-2 (0.314 g-0.628 g)once, 3 times a day, for 8 weeks. Extracorporeal shock wave(ESW)group was given the impact frequency of 7 Hz, healing energy to choose 1-2 bar, every part, under the shock of 2000 per week, 8 times for one course of treatment. Before and after a course of treatment,for the two groups of patients,we evaluated the visual analog pain score (visual analog scale, VAS), knee functional score (Western Ontario and McMaster University Osteoarthritis Index, WOMAC) and measurement of 50 meters walking time.Results The two groups of patients did not have serious adverse reactions. ESW group of patients had a different degree of pain symptoms relief, the average VAS pain score (3.2±2.4) before the treatment (6.8±2.2) decreased significantly (P<0.05). The knee joint function was improved; the WOMAC index (P<0.05). 50 meters walking time (37.0±6.3 s) before the treatment (39.9±7.7 s) have significantly reduced (P<0.05). In control group,VAS pain score, the knee joint function, 50 meters walking time had no obvious improvement.Conclusion Compared with oral glucosamine, ESWT for treatment of knee osteoarthritis in elderly women has no side effects, can relieve pain, restore joint function and can be selected as a new treatment for osteoarthritis.
关键词
女性 /
膝骨性关节炎 /
体外冲击波 /
功能评分
Key words
female /
knee osteoarthritis /
extracorporeal shock wave /
function scores
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