目的 应用冠状动脉CT血管成像(computed tomography angiography，CTA)确定有高危因素且非糖尿病无冠心病症状者冠状动脉粥样硬化(coronary atherosclerotic， CA)管腔狭窄程度，评价其与高危因素的相关性。方法 在非糖尿病无冠心病症状健康查体的人群中，收集有高危因素(性别、年龄、高血压、高脂血症)者，并将其分为单项高危因素组、多项高危因素(2项及以上高危因素)组。统计有高危因素者冠状动脉粥样硬化管腔狭窄程度。结果 单项及多项高危因素各组，管腔狭窄程度为Ⅰ级的发病率最高，随年龄的增长，管腔狭窄程度为Ⅱ级、Ⅲ级的发病率也增长。有高危因素且冠状动脉粥样硬化管腔狭窄＞50%者与对照组对比，单项高危因素且＞40岁组及多项高危因素各组，冠状动脉粥样硬化管腔狭窄＞50%的发生率与对照组有显著差异(P=0.0011，P=0.048，P=0.020);单项高危因素且＜40岁组，管腔狭窄＞50%的发生率与对照组无显著差异(P=0.6013)。结论 在非糖尿病无症状人群中，冠状动脉CTA在预测冠状动脉病粥样硬化严重程度方面提供重要的信息。

Objective To make use of coronary CTA to determine the incidence rate of coronary atherosclerosis stenosis for non-diabetic asymptomatic people who have risk factors and evaluate its correlation with risk factors.Methods We recruited non-diabetic asymptomatic people who have high-risk factors (sex, age, hypertension, hyperlipidaemia) and divided them into single high-risk factor group and multiple high-risk factors group. We made statistical processing on the incidence rate of disease for people who had high-risk factors of coronary atherosclerosis.Results Single and multiple high risk factors between groups, the degree of luminal stenosis rate was highest for grade Ⅰ; along with increasing age,the incidence of class Ⅱ, Ⅲ grade luminal stenosis grew.Risk factors and coronary atherosclerosis luminal stenosis >50% compared with the control group, single risk factors and >40 years old and multiple risk factors group, incidence of coronary atherosclerosis luminal stenosis >50% had significant differences from the control group(P=0.0011,P=0.048,P=0.020). single risk factors and <40 years old groups, the incidence of coronary atherosclerosis luminal stenosis >50% had no significant difference from the control group (P=0.6013).Conclusions In asymptomatic non-diabetic population, coronary CTA in the prediction of atherosclerotic coronary artery disease severity provides important information. A large number of clinical data showed that coronary CTA can display plaque number and number of luminal stenosis ≥50%.