目的 分析探讨武警某部官兵消化性溃疡(peptic ulcer, PU)发病因素的相关危险性。方法 选择2012-01至2015-12在我院军人内科住院治疗的PU患者78例(PU组)以及同期在门诊行电子胃镜检查确诊为慢性胃炎的患者125例(对照组),分析兵龄、职务、工作性质、非甾体类抗炎药物(non-steroidal anti-inflammatory drugs,NSAIDs)服用史、PU家族史、吸烟史、饮食状况、作息状况及幽门螺旋杆菌(helicobacter pylori,HP)感染与PU发生的关系。结果 PU组中兵龄2年以上的官兵、长期担负执勤任务的官兵、HP感染者、长期服用NSAIDs、既往有PU的家族史、无规律饮食及无规律作息情况均显著高于对照组(P<0.05)。将上述危险因素进行多因素Logistics回归分析,兵龄、工作性质、PU家族史、吸烟史、NSAIDs服用史、作息状况与PU发生密切相关(P<0.05)。PU在新兵、上等兵以及中级以上士官发生率均较低,分别为6.4%、12.8%与9.0%,在初级士官的发生率则明显升高,达到71.8%,通过与对照组进行比较,两者之间的差异有统计学意义(P=0.012)。结论 兵龄、工作性质、PU家族史、吸烟史、NSAIDs服用史、作息状况与PU发生密切相关。为减少PU的发生,重点应放在初级士官以及担负执勤任务的官兵中,特别是这些人群的生活习惯。

Objective To investigate the factors associated with peptic ulcer (PU) in servicemen.Methods Seventy- eight PU patients treated in our hospital between January 2012 and December 2015 were recruited in the study while another 125 patients diagnosed with chronic gastritis during the same period were assigned as control group. Factors associated with PU including the length of military service, rank, types of work, history of non-steroidal anti-inflammatory drugs (NSAIDs) use, history of PU family, history of smoking, diet, working time and infection of helicobacter pylori (HP) were analyzed in the study.Results The cases of patients who had a length of military service longer than 2 years, or were on chronic guard duty, or tested HP positive, or took NSAIDs for a long,or had a family history of PU or a history of smoking, or had an irregular diet or irregular working time in PU group far outnumbered those in the control group(P<0.05). Logistic regression analysis showed that the length of military service, types of work, history of PU family, history of smoking, history of NSAIDs use, working time were closely associated with PU(P<0.05). The incidence of PU in privates, privates first class, and sergeants was 6.4%, 12.8%, and 9.0% respectively what that of corporals was as high as 71.8%. Compared with the control group, the difference was statistically significant (P=0.012).Conclusions Length of military service, typess of work, history of PU family, history of smoking, history of NSAIDs use, and working time were closely associated with PU. To lower the incidence of PU, we should focus our attention on corporals and those on guard duty, especially on their living habits.