目的 用沙美特罗/丙酸氟替卡松(商品名:舒利迭)联合噻托溴铵(商品名:思力华)治疗分析慢性阻塞性肺疾病(chronic obstructive pulmoriary disease, COPD)的效果。方法 选择2013-2015年确诊为COPD且接受诊治的患者60例,其中接受常规COPD对症治疗方案的患者30例为对照组,另采取沙美特罗/丙酸氟替卡松联合噻托溴铵治疗的30例为观察组。对比两组疗效。结果 对照组总有效率83.3%,观察组总有效率96.7%;观察组高于对照组,差异有统计学意义(P<0.05);观察组FEV1和FEV1/FVC均大于对照组,差异有统计学意义(P<0.05);治疗后5个月检测6 min步行距离和生活质量情况,观察组均优于对照组,差异有统计学意义(P<0.05)。结论 用沙美特罗/丙酸氟替卡松联合噻托溴铵方案治疗COPD能提高临床疗效和促进身体功能恢复。
Abstract
Objective To analyze the clinical significance of treatment of patients with chronic obstructive pulmonary disease (COPD) with seretide combined with spiriva.Methods Sixty patients diagnosed with chronic obstructive pulmonary disease (COPD) and treated between 2013 and 2015 were selected as subjects. Thirty of them received conventional treatment and served as control group while the rest took seretide and spiriva and served as observation group. The clinical efficacy of different intervention programs was compared.Results After treatment, the total effective rate was 83.3% in control group, butwas 96.7% in observation group,and the difference was statistically significant (P<0.05). FEV1 and FEV1/FVC of observation group were greater than those of control group, and the difference was statistically significant (P<0.05). After 5 months of treatment,the therapeutic effect was better in observation group than in control group in terms of the 6 min walking distance and quality of life (P<0.05), and the difference was statistically significant.Conclusions In patients with chronic obstructive pulmonary disease (COPD), treatment with seretide combined with spiriva can significantly improve clinical efficacy and recovery of physical functions of patients.
关键词
舒利迭 /
思力华 /
慢性阻塞性肺疾病
Key words
Sulidie /
Spiriva /
chronic obstructive pulmonary disease
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 周新锋, 夏晓东. 舒利迭联合噻托溴铵对稳定期中重度慢性阻塞性肺疾病患者肺功能的影响[J]. 中国现代医生, 2015, 53(23):28-30.
[2] 刘建民, 涂 强. 慢性阻塞性肺疾病老年患者稳定期联合应用舒利迭和思力华的观察[J]. 江西医药, 2015,50(1):54-56.
[3] 韩 辉. 舒利迭联合思力华治疗对稳定期慢性阻塞性肺疾病患者的疗效及肺功能的影响[J]. 实用临床医药杂志, 2016,20(3): 242-245.
[4] 徐胜辉. 思力华联合舒利迭治疗稳定期慢性阻塞性肺病的临床分析[J].当代医学,2015,21(10):153-154.
[5] 李直苹. 舒利迭联合思力华治疗 COPD 临床效果初步评价及分析[J]. 中国实用医药, 2016,8(1):9-10.
[6] 黄 富, 梁永祥, 梁 健,等. 吉诺通联合舒利迭治疗慢性阻塞性肺疾病急性加重期的临床效果观察[J]. 吉林医学, 2015, 36(4): 623-625.
[7] 代雯文. 西医综合疗法在慢阻肺合并呼竭中的临床效果观察[J]. 世界最新医学信息文摘(连续型电子期刊), 2016, 16(15):1321-1323.
[8] 王晓红, 高 颖. 无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的疗效观察[J]. 中国药物与临床, 2014,14(1):81-83.