目的 分析前列腺特异性抗原(prostate specific antigen, PSA)异常患者的穿刺结果与相关影响因素。方法 对首都医科大学密云教学医院2014-01至2016-10行前列腺穿刺的87例患者进行回顾性分析,应用单因素和多因素Logistic回归分析年龄、体重指数、导尿、尿中白细胞增高、血脂、tPSA、f/t、前列腺体积和PSA密度等因素。结果 发现LDL-C≥2.50 mmol/L的患者,则穿刺结果为前列腺癌的风险是LDL-C＜2.50 mmol/L患者的0.140倍(95%CI 0.026～0.747);前列腺体积为20～45 ml和≥45 ml时,则穿刺结果为前列腺癌的风险分别是体积＜20 ml的患者的0.084倍(95%CI 0.007～0.9530)和0.039倍(95%CI 0.003～0.465)。结论 血脂LDL-C水平越低和前列腺体积越小,确诊前列腺癌的风险越大。
Abstract
Objective To analyze the outcomes of biopsy in patients with abnormal PSA and influencing factors.Methods Data on eighty-seven cases of prostate biopsy patients who had undergone prostate biopsy at our hospital between January 2014 and October 2016 was retrospectively analyzed. Univariate and multivariate logistic regression analysis was used to analyze such factors as age, body mass index, catheterization, urinary white blood cell increase, blood lipids, tPSA, f/t, prostate volume and PSA density.Results LDL-C(OR:0.140,95%CI 0.026-0.747) and prostate volume(OR:0.084, 95%CI 0.007-0.9530; OR:0.039, 95%CI 0.003-0.465)were significantly associated with prostate cancer.Conclusions We have confirmed that the lower the LDL-C level and the smaller the prostate volume, the greater the risk of prostate cancer.
关键词
前列腺穿刺 /
前列腺特异性抗原 /
Logistic回归分析 /
前列腺癌
Key words
prostate biopsy /
PSA /
logistic regression analysis /
prostate cancer
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