目的 探讨非酒精性Wernicke 脑病的临床特点,以提高对该种脑病的认识。方法 对20例非酒精性Wernicke 脑病患者的相关临床资料进行回顾性分析。结果 经补充维生素B1治疗后,20例患者中,10例患者治愈;7例患者好转,但遗留不同的神经系统后遗症;2例患者死亡;1例胃癌术后复发患者放弃治疗。结论 Wernicke 脑病起病隐匿,临床表现不典型且多样化,容易被漏诊及误诊,早期诊断、及时有效地补充维生素B1能有效改善此病预后。
Abstract
Objective To explore the clinical features,results of laboratory examinations and image manifestations of non-alcoholic Wernicke’s encephalopathy so as to update our knowledge of the disease for early diagnosis.Methods Clinical data of twenty patients with non-alcoholic Wernicke’s encephalopathy were analyzed retrospectively.Results After the supplement treatment with vitamin B1, ten patients were cured,seven got better but with different neurological sequelae, two died, and one gave up treatment following recurrence of gastric cancer.Conclusions Non-alcoholic Wernicke’s encephalopathy is a disease with delitescent onset and complicated clinical manifestations so that misdiagnosis is not uncommon. Early diagnosis and timely supplement treatment with vitamin B1 can be the key to better prognosis.
关键词
Wernicke 脑病 /
非酒精性 /
维生素B1
Key words
Wernicke’s encephalopathy /
non-alcoholic /
vitamin B1
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