目的 探讨急性原发性胼胝体变性的MRI表现,提高对该病的认识和诊断水平。方法 回顾性分析2016-01至2017-05经临床证实的急性原发性胼胝体变性31例患者的临床资料及影像资料。结果 急性原发性胼胝体变性多见于胼胝体压部 (13/31, 41.9%),MRI示呈等长T1、长T2信号改变,DWI呈高信号及稍高信号。20例出现胼胝体以外脑实质病变,多见于半卵圆中心(20/31, 64.5%)和额顶叶白质(18/31, 58.1%)。结论 MRI能清晰显示胼胝体及以外病灶,影像表现具有一定的特异性,MRI对其早期诊断、治疗及预后具有重要价值,可作为临床首选检查。
Abstract
Objective To analyze the MRI features of acute Marchiafava-Bignami disease(MBD)and improve the literacy and diagnosis of this disease.Methods The MRI images and clinical data of 31 cases of Marchiafava-Bignami disease proved by clinical data between January 2016 and May 2017 were retrospectively analyzed.Results Acute primary Marchiafava-Bignami disease was more common in the splenium of the corpus callosum (13/31, 41.9%). MRI showed changes in T1 and T2 signals of equal length. DWI showed high signals and slightly high signals. Twenty cases showed brain parenchymal lesions outside the corpus callosum, which were more common in semi-oval centers (20/31, 64.5%) and fronto-parietal white matter (18/31, 58.1%).Conclusions MRI can clearly show the corpus callosum and other lesions. The imaging features are specific to some extent. MRI is of great value for the early diagnosis, treatment and prognosis of this disease, which can be used as the first choice for clinical examination.
关键词
胼胝体变性 /
磁共振成像 /
弥散加权成像
Key words
Marchiafava-Bignami disease /
magnetic resonance imaging /
diffusion weighted imaging
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参考文献
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基金
河北省张家口市级科技计划自筹经费项目(1621118H)
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