目的 探讨迈瑞公司labXpert系统在血细胞分析自动审核中的应用。方法 选择2017年6－7月采用迈瑞公司labXpert(专家系统)软件审核的血常规数据进行分析。主要包括:(1)统计总体自动审核比例;(2)对违反复检规则的样本进行分析,分析违反规则的样本构成;(3)随机分析800例血常规样本周转时间(TAT)平均值、中位数,并将自动审核与传统审核方式进行对比;(4)统计TAT超过30 min的比例,并将该群样本构成进行分析。结果 共统计10 860例血常规标本,自动审核通过率为84.2%;违反复检规则主要样本类型为:未成熟粒细胞报警提示及数目、WBC超范围(WBC<4.0×10⁹/L或>30×10⁹/L)及反应性淋巴细胞报警提示等相关规则。自动审核TAT中位数为20 min, TAT超过30 min比例为20.63%;传统审核TAT中位数为26 min, TAT超过30 min比例为30.25%;自动审核与传统审核比较,差异有统计学意义(P<0.05)。TAT超时的样本中,WBC系异常最多(P<0.05),其次为RBC系异常及PLT系异常。结论 采用专家系统软件对标本进行自动审核,在保证报告质量同时可以提高工作效率,缩短TAT时间,实验室可以采用该软件对异常构成进行分析,有针对性地优化血常规分析流程。

Objective To explore the applicability of Mindray’s LabXpert System in automatic checking of routine blood tests.Methods Between June and July 2017, Mindray’s LabXpert (the Expert System) software was used to analyze the data on blood routine tests, involving counting the overall proportion of automatic check, analyzing the composition of samples which violated the re-examination rules,randomly analyzing the mean and median turnover time (TAT) of 800 blood samples by comparing the automatic check with the traditional check method, and by counting the samples whose TAT was over 30-min.Results A total of 10,860 blood samples were collected and the pass rate of automatic check reached 84.2%.The composition of samples that violated the re-inspection rules was analyzed.The main types of samples that violated the re-inspection rules were immature granulocyte warning and the number of immature granulocytes, WBCs which were beyond the normal range (WBC<4.0×10⁹/L or>30×10⁹/L) and reactive lymphocyte warning and other related rules.The average TAT of the automatic method was 20 minutes, while the percentage of TAT over 30 minutes was 20.63%.The average TAT of the traditional method was 26 minutes, and the proportion of TAT over 30 minutes was 30.25%, so the difference was statistically significant (P<0.05).Among the samples with overtime TAT , WBC-related parameters were the most abnormal(P<0.05), followed by RBC-related parameters and PLT-related parameters.Conclusions The Expert System software, when used to automatically check samples, can improve the work efficiency, shorten the time of TAT and guarantee the quality of reports.A laboratory can use this software to analyze the abnormal components and optimize the blood routine analysis process.