目的 观察ReCell技术移植治疗稳定期白癜风的临床疗效。方法 选择2015-07至2017-07稳定期白癜风患者21例,黑素细胞来源采用正常皮肤发疱的方法,应用ReCell技术将疱壁制成含有黑素细胞的表皮细胞混悬液,将表皮细胞混悬液种植于白斑皮损创面,移植后观察临床治疗效果。结果 21例白癜风患者中的33块白癜风皮损进行了移植治疗,移植后皮损均出现程度不等的复色,移植后6个月的3、4级复色率达87.09%,移植后未见不良反应。结论 应用ReCell技术移植治疗稳定期白癜风,具有移植区复色效果好、供皮区不留瘢痕的优点,并且临床上安全性可靠,操作相对简单,不需要专门的实验室,值得临床推广应用。
Abstract
Objective To explore the clinical efficacy of grafting treatment of stable vitiligo with ReCell technology.Methods Twenty-one patients of stable vitiligo were selected between 2015 and 2017. The melanocytes were taken from suction skin blisters on the abdomen wall. The non-cultured melanocyte-keratinocyte suspension was prepared with ReCell technology before the cell suspension was grafted onto vitiliginous lesions.Results Thirty lesions from 21 vitiligo patients were treated with cell suspension grafting. There was repigmentation to different extents in all the patients after operation. The total rate of repigmentation of grade 3 to 4 was 87.09% after six months.Conclusions When ReCell technology is used for grafting treatment of vitiligo, the repigmentation efficacy is excellent, and no scar is formed in suction blisters. This approach is relatively simple and reliable without the need for a special laboratory.
关键词
白癜风 /
ReCell技术 /
移植治疗
Key words
vitiligo /
ReCell technology /
grafting
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参考文献
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基金
首都临床特色应用研究科研课题(Z141107002514170)
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