目的 总结肾移植术后尿路上皮肿瘤的临床特点及诊治体会。方法 回顾性分析清华大学第一附属医院和解放军总医院第三医学中心2004-07至2017-12收治的31例肾移植术后尿路上皮肿瘤患者的临床资料。结果 31例肾移植术后尿路上皮肿瘤患者中,男10例,女21例,15例为输尿管肿瘤,7例为膀胱肿瘤,3例膀胱肿瘤同时合并输尿管肿瘤,5例肾盂肿瘤,1例移植肾肾盂癌。患者均接受手术治疗,其中17例患者术后肿瘤复发而再次接受手术治疗。随访期内6例因肿瘤复发死亡,1例因肠梗阻伴脓毒症死亡。结论 肾移植受者更易发生肿瘤,应早期诊断并根据肿瘤特点尽早采取积极的手术治疗措施。
Abstract
Objective To summarize the clinical characteristics, diagnosis, treatment and prognosis of urothelial neoplasms in renal transplantation recipients.Methods The clinical data on thirty-one cases of urothelial neoplasms following renal transplantation treated between July 2004 and December 2017 was retrospectively analyzed. The clinical characteristics of the disease, therapies and subsequent oncologic outcomes were compared.Results Among the thirty-one cases, ten were males and the rest were females. Fifteen of them had ureter urothelial neoplasms, seven had urothelial neoplasms from the bladder, three had urothelial neoplasms from both the ureter and bladder, five had pelvis urothelial neoplasms, and one had urothelial neoplasms from the transplanted renal pelvis. All the cases received surgical operations and seventeen received a second operation because of tumor recurrence during the follow-up. Seven of these cases died, including six from tumor progression and one from intestinal obstruction and sepsis.Conclusions The incidence of urothelial neoplasms following renal transplantation increases, and the best treatment is early diagnosis and early surgical resection.
关键词
肾移植 /
泌尿系肿瘤 /
肿瘤
Key words
kidney transplantation /
urologic neoplasms /
neoplasms
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参考文献
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基金
北京市朝阳区科技计划项目(CYSF1822)
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