目的 探讨冠心病与老年认知功能障碍的相关性。方法 选择2018-01至2019-04医院老年科、心内科住院及体检中心老年患者共计606例,进行简易精神状况量表(MMSE)、临床痴呆评定量(CDR)、日常生活能力量表(ADL)检查,按是否患有冠心病分为冠心病组(186例)和对照组(420例),分析冠心病是否对 MMSE评分、认知功能程度存在影响,探讨冠心病和老年认知功能障碍相关性。结果 冠心病组MMSE 评分(26.18±3.21)分,CDR 评分(0.40±0.59)分,ADL评分(22.29±4.14)分 ,对照组MMSE 评分(27.18±3.36)分,CDR 评分(0.17±0.37)分,ADL评分(21.31±3.92)分,冠心病组MMSE、CDR、ADL评分明显高于对照组,差异有统计学意义(P<0.05);冠心病组与对照组认知功能程度构成比比较,差异有统计学意义(P<0.05)。结论 冠心病和老年认知功能障碍关系密切,临床上应关注两者共同的危险因素及影响因素。老年冠心病患者中应注意筛查认知功能状况并进行干预。
Abstract
Objective To explore the relationships between coronary heart disease and cognitive dysfunction in the elders.Methods A total of 606 cases of elderly patients from the Department of Geriatrics, Department of Cardiology and Center for Medical Examination were chosen between January 2018 and April 2019. The mini mental state scale (MMSE), clinical dementia rating (CDR) and activity of daily living (ADL) scale were used for the survey. According to the occurrence of coronary heart disease (CHD), these cases were divided into the CHD group (n=186) and control group (n=420). The effect of (CHD) on MMSE scores and cognitive function was studied while the correlation between CHD and cognitive dysfunction was analyzed.Results In the CHD group, the MMSE score 26.18±3.21, and CDR score was 0.40±0.59, ADL score was 22.29±4.14, compared to 27.18±3.36, 0.17±0.37, and 21.31±3.92 in the control group. The difference in MMSE, CDR and ADL scores between the two groups was statistically significant (P<0.05). The difference in cognitive function between the two groups was also statistically significant (P<0.05), suggesting that CHD was associated with cognitive dysfunction in senior citizens.Conclusions Coronary heart disease is closely related to cognitive dysfunction in the elders, so attention should be paid to the common risk factors and influencing factors in clinical practice. In elderly patients with coronary heart disease, the screening of cognitive function and intervention are necessary.
关键词
冠心病 /
老年认知功能障碍 /
相关性
Key words
coronary heart disease /
cognitive dysfunction in the elders /
correlation
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参考文献
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基金
四川省卫生和计划生育委员会重点研究项目(18ZD006)
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