目的 探讨银屑病患者生活质量和心理健康状况,为进行心理干预提供依据。方法 对2019年1—12月在解放军总医院第三医学中心皮肤科就诊的银屑病患者,采用中文版皮肤病生活质量指数调查表(dermatology life quality index,DLQI)评估银屑病患者的生活质量,采用焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS)评估银屑病患者的心理健康状况。结果 单因素方差分析显示不同性别、年龄、受教育程度、疾病分型、严重程度、病程长短对银屑病患者生活质量有不同程度影响,差异均有统计学意义(P<0.05)。女性、年龄18~30岁、高学历、红皮型、PASI评分高是银屑病患者生活质量差的危险因素。65.17%的银屑病患者存在不同程度的焦虑状态,54.45%的银屑病患者存在不同程度的抑郁状态,红皮型银屑病患者的焦虑及抑郁程度均较其他三种类型更为严重,PASI评分越高,焦虑及抑郁量表均值越高,差异具有统计学意义(P<0.05)。结论 银屑病患者生活质量受到不同程度的影响,存在焦虑、抑郁等心理问题,应进行早期心理干预。
Abstract
Objective To investigate the life quality and mental health of patients with psoriasis in order to provide data for the selection of intervention methods.Methods The Dermatology Life Quality Index (DLQI) was used to evaluate the life quality of psoriatic patients. The Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were employed to assess the mental health of psoriatic patients.Results 91.07% of the patients had their life quality affected to some extent, 29.46% of whom were moderately affected and 18.75% were severely affected. Univariate analysis of variance showed that the effects on the life quality of patients with psoriasis (P<0.05) varied according to gender, age, education levels, types or severity of psoriasis and duration of the disease. Risk factors for the poor life quality of patients included femininity, 18 to 30 years of age, high education levels, the erythroid type and high PASI scores. 65% of these psoriatic patients had different levels of anxiety, and 54% of them showed depression to different extents. Patients with erythrodermic psoriasis displayed more severe anxiety and depression than those with the other three types of psoriasis, and the difference was statistically significant (P<0.05). Additionally, the higher the PASI score, the more serious the condition, and the higher mean value of anxiety and depression scale. The difference was also statistically significant (P<0.05).Conclusions Patients’ life quality is affected by psoriasis to different degrees, and their mental health is usually poor, most of whom have such psychological problems as anxiety and depression. Health-care providers should care for not only physical treatment but also the mental health of patients. Early psychological intervention is recommended.
关键词
银屑病 /
生活质量 /
心理健康 /
影响因素
Key words
psoriasis /
life quality /
mental health /
influencing factors
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Korman N J. Management of psoriasis as a systemic disease: what is the evidence? [J].Br J Dermatol,2020,182(4):840-848.
[2] Jasmina M, Mufida Z, Arzija P, et al. Correlation between quality of life and depression among persons suffering from psoriasis[J].Med Arch,2017,71(5):341-346.
[3] 汪向东,王希林,马 弘.心理卫生评定量表手册(增订版)[M].北京:中国心理卫生出版杂志社,1999:325.
[4] 舒 心,王 睿,黄 敏,等.代谢组学研究技术及其在银屑病研究中的应用进展[J].武警医学,2020,31(7):625-629.
[5] Zhenli K,Yii B B,Leng L T,et al.Determinants of quality of life and psychological status in adults with psoriasis[J].Arch Dermatol Res,2018,310(5):443-451.
[6] Jung S, Lee S M, Suh D, et al. The association of socioeconomic and clinical characteristics with health-related quality of life in patients with psoriasis: a cross-sectional study[J].Health Qual Life Outcomes,2018,16(1):180.
[7] Jauhar M K,Muhammad U R,Moizza T, et al.Dermatology life quality index in patients of psoriasis and its correlation with severity of disease[J].J Ayub Med Coll Abbottabad,2020,32(1):64-67.
[8] Gelfand J M, Feldman S R, Stern R S, et al. Determinants of quality of Life in patients with psoriasis:a study from the US population[J].J Am Acad Dermatol,2004,51(5):704-708.
[9] Sultana A,Bhuiyan S I,Mahmud M M,et al. Comorbidities in patients with psoriasis[J].Mymensingh Med J,2019,28(4):894-899.
[10] Altunay I K,Atis G,Esen K, et al. Impact of functional pruritus compared with mild psoriasis on quality of life: a cross-sectional questionnaire study in Turkey[J].Am J Clin Dermatol,2014,15(4):365-370.
[11] 杨颜龙,张 禁,易松柏,等. 阿维A 胶囊联合复方甘草酸苷注射液治疗红皮病型银屑病30例临床观察[J].中国皮肤性病学杂志,2015,22(2):217-220.
[12] Jasmina M,Mufida Z,Arzija P,et al.Correlation between quality of life and depression among persons suffering from psoriasis[J].Med Arch,2017,71(5):341-346.
[13] Souza C S,Castro C S, Carneiro R O,et al.Metabolic syndrome and psoriatic arthritis among patients with psoriasis vulgaris:quality of life and prevalence[J].J Dermatol,2019,46(1):3-10.
[14] José M, Paloma N,José E M,et al.Quality of life, anxiety and depressive symptoms in patients with psoriasis: a case-control study[J].J Psychosom Res,2019,124:109780.
[15] 石继海,夏隆庆.不同严重程度银屑病对患者生活质量的影响[J].中华皮肤科杂志,2003,36(3):156-158.
[16] 赵 辩.中国临床皮肤病学[M].2版.南京:江苏凤凰科学技术出版社,2017:1112.
基金
首都特色临床应用研究(Z181100001718013)