目的 观察415 nm蓝光联合5%过氧苯甲酰凝胶治疗轻中度寻常性痤疮的临床疗效与安全性。方法 选取武警湖北总队医院2019-03至2020-09轻中度寻常性痤疮90例,随机分为3组,每组30例。联合组同时予415 nm蓝光照射联合5%过氧苯甲酰凝胶外用;蓝光组和药物组分别予415 nm蓝光照射和5%过氧苯甲酰凝胶外用。3组均在治疗8周后判定疗效。结果 治疗8周后联合组有效率为83.3％。蓝光组和药物组有效率分别为30％和56.7％,与联合组有效率比较,差异均有统计学意义。治疗过程中不良反应少见且患者均可耐受。结论 415 nm蓝光联合5%过氧苯甲酰凝胶治疗轻中度寻常性痤疮疗效显著,不良反应少。
Abstract
Objective To observe the efficacy of 415 nm blue light and 5% benzoyl peroxide gel in the treatment of acne vulgaris. Methods Ninety cases of acne vulgaris were randomly divided into three groups. The patients of the combination group were treated with both 415 nm blue light and 5% benzoyl peroxide gel while the blue light group and the medication group were treated with 415nm blue light and 5% benzoyl peroxide gel respectively. The clinical effect was observed after 8 weeks of treatment. Results The effective rate of the combination group was 83.3％, compared with 30.0％ and 56.7％ respectively in the blue light group and drug group. Besides, the adverse reactions were mild and tolerable in the combination group. Conclusions The combination of 415 nm blue light and 5% benzoyl peroxide gel is an effective and safe approach to acne vulgaris.
关键词
寻常性痤疮 /
415 nm蓝光 /
5%过氧苯甲酰凝胶
Key words
acne vulgaris /
415nm blue light /
5% benzoyl peroxide gel
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