臭氧疗法治疗神经系统疾病的作用机制研究进展

孙闻, 徐龙河, 刘永哲

武警医学 ›› 2022, Vol. 33 ›› Issue (10) : 907-910.

PDF(947 KB)
PDF(947 KB)
武警医学 ›› 2022, Vol. 33 ›› Issue (10) : 907-910.
综述

臭氧疗法治疗神经系统疾病的作用机制研究进展

  • 孙闻1,2, 徐龙河2 综述, 刘永哲2 审校
作者信息 +
文章历史 +

引用本文

导出引用
孙闻, 徐龙河, 刘永哲. 臭氧疗法治疗神经系统疾病的作用机制研究进展[J]. 武警医学. 2022, 33(10): 907-910
中图分类号: R741   

参考文献

[1] Farpour H R, Ashraf A, Hosseini S S. The efficacy of ozone prolotherapy compared to intra-articular hypertonic saline injection in reducing pain and improving the function of patients with knee osteoarthritis: a randomized clinical trial[J].Evid Based Complement Alternat Med, 2021,2021:5579944.
[2] Scassellati C, Galoforo A C, Bonvicini C, et al.Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders[J].Ageing Res Rev, 2020,63:101138.
[3] Mlá E, Croce E, Moviglia M T, et al.Ozone as Modulator of resorption and inflammatory response in extruded nucleus pulposus herniation. revising concepts[J].Int J Mol Sci, 2021,22(18):9946.
[4] Moghadam M T, Dadfar R, Khorsandi L. The effects of ozone and melatonin on busulfan-induced testicular damage in mice[J].JBRA Assist Reprod, 2021,25(2):176-184.
[5] Sen S, Sen S. Ozone therapy a new vista in dentistry: integrated review[J].Med Gas Res, 2020,10(4):189-192.
[6] Sconza C, Respizzi S, Virelli L, et al.Oxygen-ozone therapy for the treatment of knee osteoarthritis: a systematic review of randomized controlled trials[J].Arthroscopy, 2020,36(1):277-286.
[7] Lin S Y, Ma J, An J X, et al.Ozone Inhibits APP/Aβ production and improves cognition in an app/ps1 transgenic mouse model[J].Neuroscience, 2019,418:110-121.
[8] Solleiro V H, Rivas A S. Effect of chronic oxidative stress on neuroinflammatory response mediated by cd4(+)t cells in neurodegenerative diseases[J].Front Cell Neurosci, 2018,12:114.
[9] Zhang W, Wang F, Zhang L, et al.Intrathecal injection of ozone alleviates CCIinduced neuropathic pain via the GluR6NFκB/p65 signalling pathway in rats[J].Mol Med Rep, 2021,23(4);231.
[10] Scassellati C, Galoforo A C, Esposito C, et al.Promising intervention approaches to potentially resolve neuroinflammation and steroid hormones alterations in alzheimer's disease and its neuropsychiatric symptoms[J].Aging Dis, 2021,12(5):1337-1357.
[11] Wang J, Wu M, Lin X, et al.Low-concentration oxygen/ozone treatment attenuated radiculitis and mechanical allodynia via PDE2A-cAMP/cGMP-NF-κB/p65 signaling in chronic radiculitis rats[J].Pain Res Manag, 2018,2018:5192814.
[12] Zhu L, Ding S, Xu L, et al.Ozone treatment alleviates brain injury in cerebral ischemic rats by inhibiting the NF-κB signaling pathway and autophagy[J].Cell Cycle, 2022,21(4):406-415.
[13] 赵冬凤, 刘 强, 陈 丽, 等. 医用臭氧疗法治疗卒中后抑郁患者的临床疗效评价[J].中国社区医师, 2021,37(1):54-55.
[14] Izadi M, Tahmasebi S, Pustokhina I, et al.Changes in Th17 cells frequency and function after ozone therapy used to treat multiple sclerosis patients[J].Mult Scler Relat Disord, 2020,46:102466.
[15] Tahmasebi S, Qasim M T, Krivenkova M V, et al.The effects of oxygen-ozone therapy on regulatory T-cell responses in multiple sclerosis patient[J].Cell Biol Int, 2021,45(7):1498-1509.
[16] Delgado R L, Riera M, Mesta F, et al.Medical ozone promotes Nrf2 phosphorylation reducing oxidative stress and pro-inflammatory cytokines in multiple sclerosis patients[J].Eur J Pharmacol, 2017,811:148-154.
[17] Singh A, Kukreti R, Saso L, et al.Oxidative stress: a key modulator in neurodegenerative diseases[J].Molecules, 2019,24(8):1583.
[18] Viebahn H R, León O S. Ozone in medicine. the low-dose ozone concept and its basic biochemical mechanisms of action in chronic inflammatory diseases[J].Int J Mol Sci, 2021,22(15):7890.
[19] Castro S L, Tapias V, Gathagan R, et al.Blueberry juice augments exercise-induced neuroprotection in a Parkinson's disease model through modulation of GDNF levels[J].IBRO Neurosci Rep, 2022,12:217-227.
[20] 邓兵梅, 杨红军, 彭凯润, 等. 臭氧对PD模型大鼠黑质氧化应激及凋亡相关蛋白表达的影响[J].中华神经医学杂志, 2014,13(12):1223-1227.
[21] 税云华, 张 兰, 雷光磊, 等. 臭氧大自血法对睡眠剥夺大鼠褪黑素及氧化应激指标的影响[J].实验动物与比较医学, 2020,40(2):110-115.
[22] Karademir M, Sonmez M A, Akcilar R, et al.Evaluation of therapeutic potential of intraperitoneal ozone gas in combination with insulin above cranial and spinal neuropathy in rats with diabetes mellitus[J].Bratisl Lek Listy, 2018,119(10):636-641.
[23] Cai H A, Tao X, Zheng L J, et al.Ozone alleviates ischemia/reperfusion injury by inhibiting mitochondrion-mediated apoptosis pathway in SH-SY5Y cells[J].Cell Biol Int, 2020,44(4):975-984.
[24] Wu M Y, Xing C Y, Wang J N, et al.Therapeutic dosage of ozone inhibits autophagy and apoptosis of nerve roots in a chemically induced radiculoneuritis rat model[J].Eur Rev Med Pharmacol Sci, 2018,22(6):1787-1797.
[25] Resitoglu B, Celik Y, Komur M, et al.The efficacy of ozone therapy in neonatal rats with hypoxic ischemic brain injury[J].Bratisl Lek Listy, 2018,119(2):81-85.
[26] Abati E, Bresolin N, Comi G, et al.Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS)?[J].Expert Opin Ther Targets, 2020,24(4):295-310.
[27] Bette M, Cors E, Kresse C, et al.Therapeutic treatment of superoxide dismutase 1 (g93a) amyotrophic lateral sclerosis model mice with medical ozone decelerates trigeminal motor neuron degeneration, attenuates microglial proliferation, and preserves monocyte levels in mesenteric lymph nodes[J].Int J Mol Sci, 2022,23(6):3403.
[28] Costanzo M, Boschi F, Carton F, et al.Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells[J].Eur J Histochem, 2018,62(3):2969.
[29] Tricarico G, Isakovic J, Song M S, et al.Ozone influences migration and proliferation of neural stem cells in vitro[J].Neurosci Lett, 2020,739:135390.
[30] Baeza N J, Pinto B R. Systemic review: ozone: a potential new chemotherapy[J].?Int J Mol Sci, 2021,22(21):11796.
[31] Braidy N, Izadi M, Sureda A, et al.Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain[J].J Cell Physiol, 2018,233(4):2705-2714.

基金

军队保健课题(21BJZ28)

PDF(947 KB)

Accesses

Citation

Detail

段落导航
相关文章

/