目的 评价智能分光比色技术(FICE)放大胃镜联合胃泌素-17(G-17)对早期胃癌及其癌前病变的诊断价值。方法 选取2017-01至2020-01于武警四川总队医院接受胃镜检查患者260例,采用FICE放大内镜联合检测空腹血清G-17,分析该方法对早期胃癌及其癌前病变的诊断效能。结果 与普通放大内镜相比,FICE放大内镜对胃黏膜微细血管形态结构、腺管开口的显示图像清晰度增加(P<0.05)。FICE放大内镜联合G-17检查诊断早期胃癌的敏感性为91.94%,特异性为98.48%,准确性为96.92%,高于FICE放大内镜(敏感性64.52 %,特异性98.99 %,准确性90.77 %)。结论 FICE放大内镜与G-17对早期胃癌及其癌前病变有较高的筛查检出率,有一定的临床推广价值。
Abstract
Objective To analyze the diagnostic value of Fuji intelligent chromo-endoscopy (FICE) combined with gastrin-17 (G-17) for early gastric cancer and precancerous lesions. Methods Two hundred and sixty patients admitted to the hospital from January 2017 to January 2020 were selected for digestive endoscopy. FICE was used to magnify endoscopy, and the fasting serum G-17 was analyzed by enzyme linkedbent assay (ELISA). Statistical analysis of the efficacy of FICE magnifying endoscopy combined with G-17 in the diagnosis of early gastric cancer and precancerous lesions. Results Compared with conventional magnifying endoscopy, FICE could improve the image clarity of the morphology and structure of the gastric mucosa and the opening of the glandular canal (P<0.05). Sensitivity, specificity and accuracy of FICE combined with G-17 in diagnosis of early gastric cancer were 91.94%, 98.48%, and 96.92%, higher than FICE (64.52%, 98.99%, and 90.77%). Conclusions FICE magnifying endoscopy combined with G-17 has a higher screening and detection rate for early gastric cancer and precancerous lesions, which is of high clinical value.
关键词
电子分光内镜技术 /
放大内镜 /
胃泌素-17 /
胃癌 /
癌前病变
Key words
electronic spectroscopic endoscopy /
magnifying endoscope /
gastrin-17 /
gastric cancer /
precancerous lesions
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