目的 探讨2种产地不同支架机械取栓治疗急性脑梗死的临床效果和卫生经济学成本。方法 选择铁岭市中心医院收治的64例急性脑梗死患者,全部应用支架机械取栓治疗。其中进口支架组31例,使用SolitaireFR支架,国产支架组33例,使用Reco支架。应用NIHSS评分评价患者不同时间节点的神经功能,采用mRS评分评价患者预后。比较两组患者临床疗效、不良事件发生率,以及卫生经济学指标。结果 治疗前、治疗后1、90 d两组NIHSS评分比较无统计学差异,但治疗后各时点均较术前有明显改善。治疗前和治疗后90 d两组mRS评分比较,差异无统计学意义;治疗后90 d,两组mRS评分均较术前明显改善,差异有统计学意义(P<0.05)。患者住院总费用,国产支架组(6.79±1.35)万元,少于进口支架组(7.38±1.47)万元,差异有统计学意义(P<0.05)。结论 国产支架取栓治疗急性脑梗死安全有效,经济效益明显。
Abstract
Objective To compare the clinical effect and cost of two types of stents for mechanical thrombectomy against acute cerebral infarction. Methods Sixty-four patients with acute cerebral infarction treated in Tieling Central Hospital between January 2019 and January 2021 were retrospectively enrolled, all of whom received mechanical thrombectomy. Thirty-one of these patients were treated with imported Solitaire FR stents and 33 with domestic Reco stents. NIHSS scores at different time points and mRS scores were collected to assess the neurological function and clinical outcomes of patients respectively. The clinical efficacy, incidence of adverse reactions and health-economic indexes were analyzed and compared between the two groups. Results There was no significant difference in NIHSS scores between the two groups before treatment and 90 days after treatment. The NIHSS scores were improved in both groups after treatment. No significant difference was found in terms of mRS scores between the two groups before treatment and 90 days after treatment. The mRS scores in both groups were significantly decreased 90 days after treatment (P<0.05). The average total cost of hospitalization was ( 60.790±10.350) yuan in the domestic stent group, compared with (70.380±10.470) yuan in the imported stent group, so the difference in medical costs was significant between the two groups(P<0.05). Conclusions Mechanical thrombectomy with home-made stents is more effective and safer for acute cerebral infarction.
关键词
急性脑梗死 /
支架 /
神经功能 /
卫生经济学
Key words
acute cerebral infarction /
stents /
neurologic function /
health economics
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