目的 探讨某三甲医院对重点监控药品实施药事管理措施的效果,为促进重点监控药品的合理用药提供参考。方法 某院自2020年起通过建立重点监控药品目录、设立监控指标、开展专项点评、纳入绩效考核等措施对重点监控药品实施药事管理,对2019-2022年重点监控药品品规数、采购金额、用药金额占总药品用药金额比值、住院患者使用率和平均用药金额等数据指标进行对比分析。结果 某院重点监控药品品规数由2019年的40个逐年下降至2022年的26个;采购金额下降66.42%;用药金额占比从10.59%下降至6.46%;住院患者使用率从70.51%下降至44.59%,住院患者平均用药金额从2104.65元下降至1515.08元,降幅28.01%。结论 通过系列药事管理措施,该院重点监控药品的各项用药指标均明显下降,促进临床合理用药的效果较为显著。

Objective To explore the effects of pharmaceutical administration measures on key monitored drugs in a grade Ⅲ hospital so as to provide reference for promoting rational clinical drug use. Methods From 2020, a hospital implemented pharmaceutical administration of key monitored drugs by establishing a list of key monitored drugs, setting up monitoring indicators, carrying out special comments, including performance assessment, etc. Data indicators such as the number of key monitored drugs, purchase amount, ratio of drug consumption to total drug consumption, utilization rate of inpatients and average drug consumption were compared and analyzed from 2019 to 2022. Results The number of key monitored drugs decreased from 40 in 2019 to 26 in 2022, and the purchase amount decreased by 66.42%. The proportion of drug consumption decreased from 10.59% to 6.46% with the application rate in inpatients decreasing from 70.51% to 44.59%. The average drug consumption of inpatients decreased from 2104.65 yuan to 1515.08 yuan, a decrease of 28.01%. Conclusions Through a series of pharmaceutical administration measures,the drug indexes of key monitored drugs in the hospital have decr eased significantly, and the effects of promoting clinical rational drug use is more obvious.