双生女童混合牙列期颅底形态遗传作用的纵向分析

朱常锋; 彭静

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武警医学 ›› 2023, Vol. 34 ›› Issue (3) : 238-242.

论著

双生女童混合牙列期颅底形态遗传作用的纵向分析

朱常锋¹, 彭静²

作者信息 +

Longitudinal analysis of genetic role of skull base morphology in mixed dentition girls

ZHU Changfeng¹, PENG Jing²

Author information +

文章历史 +

摘要

目的分析混合牙列期颅底形态遗传作用的纵向变化规律。方法 1994年至1999年测量89对双生女童的头颅侧位片。采用混合纵向观察法,最终得到有效双生子对数183对,其中同卵110对,异卵73对。利用双生子研究法对颅底形态作遗传和环境作用的纵向统计分析。结果颅底角度(NSBa),长度(SN,L1-2,L2+3,L2)检测到环境因素的影响(P<0.05);长度(SBa)、高度(H2)检测到遗传因素的影响(P<0.05)。结论颅底结构长度变化受较强的遗传控制,环境作用效果弱;在所有颅底部位中,蝶枕复合体受环境影响最明显,有一定临床意义;NSBa角度相对稳定,较早就确立。

Abstract

Objective To find the longitudinal genetic effects on cranial base in mixed dentition. Methods Lateral cranial radiographs of 89 pairs of twins were measured. Mixed longitudinal observation method was used to obtain 183 pairs of effective twins, including 110 identical pairs and 73 fraternal pairs. Twin study method was used to conduct the longitudinal statistical analysis of genetic and environmental effects of skull base morphology. Results Statistical comparisons revealed significant (P<0.05) environmental effects on the angle (NSBa), the depths (SN, L1-2, L2+3, L2) ; whilst genetic effects on the depth (SBa) and the height (H₂) (P<0.05). Conclusions The variation of skull base structure length is strongly controlled by heredity and weakly influenced by environment. The sphenoccipital complex is the most affected by environment among all the parts of skull base, which has certain clinical significance. NSBa Angle is relatively stable and established earlier.

导出引用

朱常锋, 彭静. 双生女童混合牙列期颅底形态遗传作用的纵向分析[J]. 武警医学. 2023, 34(3): 238-242

ZHU Changfeng, PENG Jing. Longitudinal analysis of genetic role of skull base morphology in mixed dentition girls[J]. Medical Journal of the Chinese People Armed Police Forces. 2023, 34(3): 238-242

中图分类号： R783.5

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