目的 调查北京市大兴区成人空腹血糖受损流行病学现状,在否认糖尿病病史人群中了解其空腹血糖异常的比例及其与血脂代谢的关系,为这部分人群的血糖体检筛查,以及预防发生糖尿病及心脑血管疾病提供参考。方法 2018年1-10月在中国中医科学院广安门医院体检的北京市大兴区居民共805人,采用问卷调查了解糖尿病知晓率,并检测血糖、血脂等实验室项目。结果 在698名否认糖尿病病史的受访者中,空腹血糖受损(IFG)103例(14.8%),空腹血糖(FBG)升高者130例(18.6%),与FBG正常组(541例,77.5%)相比,IFG组以及FBG升高组的三酰甘油(TG)、残粒脂蛋白(RLP)、小而密低密度脂蛋白(sdLDL-C)均显著升高(P＜0.05),高密度脂蛋白(HDL-C)则显著降低(P＜0.05)。在年龄＞60岁人群中,有糖尿病病史组的空腹血糖正常率显著高于否认有糖尿病病史组(80.8% vs. 64.4%,P=0.026)。结论 在北京市大兴区受访人群中,空腹血糖受损等血糖代谢异常的比例依然较高,且在否认糖尿病病史受访者中更为明显,并容易伴随血脂代谢异常。对血糖代谢异常的知晓、健康教育并控制高血脂等危险因素,对他们可能是干预和治疗的关键。
Abstract
Objective To provide references for glucose detection and prevention of diabetes and cardiovascular and cerebrovascular diseases.Methods From January to October 2018, a total of 805 residents in Daxing District, Beijing who had physical examinations at Guang’anmen Hospital of Chinese Academy of Traditional Chinese Medicine were enrolled. The general information was collected by questionnaires to record whether they knew that they had been diagnosed with diabetes. Blood glucose, lipid, and other laboratory test items were determined after intravenous blood collection.Results Among the 698 respondents who denied a history of diabetes, 103 fasting blood glucose cases accounted for 14.8%, and 130 higher fasting plasma glucose cases (7.0 mmol/L) accounted for 18.6%. Compared with the normal fasting glucose group, triglycerides (P<0.01), fasting plasma lipoprotein (P<0.05) and small and dense low-density lipoprotein significantly increased in the fasting glucose impaired group and higher fasting blood glucose group (P<0.05), high-density lipoprotein (HDL) significantly decreased (P<0.05). In the group older than 60, the compliance rate of fasting blood glucose in the group with diabetes history was significantly higher than that in the group with a history of diabetes mellitus (80.8% vs 64.4%, P=0.026).Conclusions Among the respondents in the Daxing District of Beijing, the proportion of impaired glucose metabolism and other abnormal glucose metabolism is still high, and it is more prevalent in the subjects who have denied a history of diabetes mellitus accompanied by abnormal blood lipid metabolism. Awareness of abnormal glucose metabolism, health education, and measures of controlling high blood lipids may be critical to the intervention and the treatment for this group of people.
关键词
空腹血糖受损 /
血脂代谢 /
糖尿病
Key words
impaired fasting glucose /
lipid metabolism /
diabetes mellitus
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