[1] 中华医学会内分泌学分会.成人甲状腺功能减退症诊治指南 [J]. 中华内分泌代谢杂志, 2017, 33(2): 167-180.
[2] Shan Z, Chen L, Lian X, et al. Iodine status and prevalence of thyroid disorders after introduction of mandatory universal salt iodization for 16 years in China: a cross-sectional study in 10 cities [J]. Thyroid, 2016, 26(8): 1125-1130.
[3] Li Y, Teng D, Ba J, et al. Efficacy and safety of long-term universal salt iodization on thyroid disorders: epidemiological evidence from 31 provinces of mainland China [J]. Thyroid, 2020, 30(4): 568-579.
[4] Xing D, Liu D, Li R, et al. Factors influencing the reference interval of thyroid-stimulating hormone in healthy adults: a systematic review and meta-analysis [J]. Clin Endocrinol (Oxf), 2021, 95(3): 378-389.
[5] Biondi B, Cappola A R, Cooper D S. Subclinical hypothyroidism: a review [J]. JAMA, 2019, 322(2): 153-160.
[6] Lou Y, Li X, Cao L, et al. LDL-cholesterol to HDL-cholesterol ratio discordance with lipid parameters and carotid intima-media thickness: a cohort study in China [J]. Lipids Health Dis, 2020, 19(1): 141.
[7] Liu X L, He S, Zhang S F, et al. Alteration of lipid profile in subclinical hypothyroidism: a meta-analysis [J]. Med Sci Monit, 2014, 20: 1432-1441.
[8] 王 欣, 任巧华, 雷 琳, 等. 老年亚临床甲状腺功能减退症血脂水平及颈动脉内膜中层厚度的研究 [J]. 中国临床保健杂志, 2019, 22(2): 212-215.
[9] Bonde Y, Breuer O, Lutjohann D, et al. Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans [J]. J Lipid Res, 2014, 55(11): 2408-2415.
[10] Gong Y, Ma Y, Ye Z, et al. Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression [J]. Metabolism, 2017, 76: 32-41.
[11] Tian L, Song Y, Xing M, et al. A novel role for thyroid-stimulating hormone: up-regulation of hepatic 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase expression through the cyclic adenosine monophosphate/protein kinase a/cyclic adenosine monophosphate-responsive element binding protein pathway [J]. Hepatology, 2010, 52(4): 1401-1409.
[12] Janovsky C, Bittencourt M S, Goulart A C, et al. Unfavorable triglyceride-rich particle profile in subclinical thyroid disease: a cross-sectional analysis of ELSA-Brasil [J]. Endocrinology, 2021, 162(2):bqaa205.
[13] 黄芳芳, 傅国胜, 汤云霞, 等. 冠心病患者亚临床甲状腺功能减退症与冠状动脉狭窄程度的相关性研究 [J]. 中华老年医学杂志, 2020, 39(5): 505-508.
[14] Ding X, Zhao Y, Zhu C Y, et al. The association between subclinical hypothyroidism and metabolic syndrome: an update meta-analysis of observational studies [J]. Endocr J, 2021, 68(9): 1043-1056.
[15] Ding X, Zhao Y, Zhu C Y, et al. The association between subclinical hypothyroidism and metabolic syndrome: an update meta-analysis of observational studies [J]. Endocr J, 2021, 68(9): 1043-1056.
[16] Ebrahimpour A, Vaghari T M, Qujeq D, et al. Direct correlation between serum homocysteine level and insulin resistance index in patients with subclinical hypothyroidism: does subclinical hypothyroidism increase the risk of diabetes and cardio vascular disease together? [J]. Diabetes Metab Syndr, 2018, 12(6): 863-867.
[17] 成晓翠, 宋林凌, 李明珍, 等. 老年痛风患者血尿酸水平与亚临床甲状腺功能减退症关系研究 [J]. 中华老年医学杂志, 2022, 41(3): 286-289.
[18] Cai P, Peng Y, Chen Y, et al. Blood pressure characteristics of subclinical hypothyroidism: an observation study combined with office blood pressure and 24h ambulatory blood pressure [J]. J Hypertens, 2021, 39(3): 453-460.
[19] Desideri G, Bocale R, D'Amore A M, et al. Thyroid hormones modulate uric acid metabolism in patients with recent onset subclinical hypothyroidism by improving insulin sensitivity [J]. Intern Emerg Med, 2020, 15(1): 67-71.
[20] Vyakaranam S, Vanaparthy S, Nori S, et al. Study of insulin resistance in subclinical hypothyroidism [J]. Int J Health Sci Res, 2014, 4(9): 147-153.
[21] Yao K, Zhao T, Zeng L, et al. Non-invasive markers of cardiovascular risk in patients with subclinical hypothyroidism: a systematic review and meta-analysis of 27 case control studies [J]. Sci Rep, 2018, 8(1): 4579.
[22] Turemen E E, Cetinarslan B, Sahin T, et al. Endothelial dysfunction and low grade chronic inflammation in subclinical hypothyroidism due to autoimmune thyroiditis [J]. Endocr J, 2011, 58(5): 349-354.
[23] Chen J, Shi M, Wang N, et al. TSH inhibits eNOS expression in HMEC-1 cells through the TSHR/PI3K/AKT signaling pathway [J]. Ann Endocrinol (Paris), 2019, 80(5-6): 273-279.
[24] Wang L, Liu J, Lu K, et al. Long non-coding RNA NEAT1 regulates endothelial functions in subclinical hypothyroidism through miR-126/TRAF7 pathway [J]. Hum Cell, 2021, 34(3): 825-835.
[25] Gupta G, Sharma P, Kumar P, et al. Study on subclinical hypothyroidism and its association with various inflammatory markers [J]. J Clin Diagn Res, 2015, 9(11): BC04-6.
[26] 李薇薇, 李惠勉. 缺血性脑卒中合并亚甲减血清TSH水平与TNF-α、Lp-PLA2、IL-6水平的相关性分析 [J]. 中华神经医学杂志, 2019,25 (11): 1124-1130.
[27] Yang C, Lu M, Chen W, et al. Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques [J]. J Exp Med, 2019, 216(5): 1182-1198.
[28] Gao F. Variation tendency of coagulation parameters in different hypothyroidism stages [J]. Acta Endocrinol (Buchar), 2016, 12(4): 450-454.
[29] Gao F, Wang G, Xu J. Alteration of hemostatic parameters in patients with different levels of subclinical hypothyroidism and the effect of l-thyroxine treatment [J]. Ann Clin Lab Sci, 2017, 47(1): 29-35.
[30] Bielecka D A, Godoy B, Suzuki T, et al. Subclinical hypothyroidism and the development of heart failure: an overview of risk and effects on cardiac function [J]. Clin Res Cardiol, 2019, 108(3): 225-233.
[31] Yao Z, Gao X, Liu M, et al. Diffuse Myocardial injuries are present in subclinical hypothyroidism: a clinical study using myocardial T1-mapping quantification [J]. Sci Rep, 2018, 8(1): 4999.
[32] 刘志浩, 倪晶宇, 郭 蕊, 等. 翻译后修饰对SERCA2a的作用在心血管疾病中的研究进展 [J]. 中华心血管病杂志, 2020, 18(2): 164-167.
[33] Dong J, Gao C, Liu J, et al. TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes [J]. Oncotarget, 2016, 26 (7): 39207-39215.
[34] Wang Y, Liu C, Liu L, et al. Association of elevated thyroid stimulating hormone with atherosclerotic cardiovascular disease and its mortality in elderly community-dwelling China [J]. Clin Interv Aging, 2022, 17: 1139-1150.
[35] Cappola A R, Fried L P, Arnold A M, et al. Thyroid status, cardiovascular risk, and mortality in older adults [J]. JAMA, 2006, 295(9): 1033-1041.
[36] Gencer B, Moutzouri E, Blum M R, et al. The impact of levothyroxine on cardiac function in older adults with mild subclinical hypothyroidism: a randomized clinical trial [J]. Am J Med, 2020, 133(7): 848-856.
[37] Zhai X, Zhang L, Chen L, et al. An Age-Specific serum thyrotropin reference range for the diagnosis of thyroid diseases in older adults: a cross-sectional survey in China [J]. Thyroid, 2018, 28(12): 1571-1579.