目的 探讨一种新型低温静脉输液装置(SY-1000型输液降温仪)对中枢性高热治疗的临床效果和安全性。方法 选取2022年1-10月在武警特色医学中心重症医学科治疗的中枢性高热患者为研究对象,按患者或家属意愿进行分组,同意采用新型低温静脉输液装置的35例为仪器组,另选择同期采用常规降温的35例为对照组。对照组常规静脉输注4 ℃液体,仪器组在仪器辅助下静脉输注4℃液体。对两组患者的体温进行动态监测,当体温降至38 ℃时停止降温。比较两组体温降至38℃所需时间、降温有效率及各组发生不良反应的情况。结果 对照组体温降至38 ℃所需时间为(6.44±0.77)h,显著长于仪器组的(4.47±0.84)h,差异有统计学意义(P＜0.05);对照组有效降温率57.14,%,显著低于仪器组的82.86%,差异有统计学意义(P＜0.05);仪器组的总不良反应发生率(22.86%)明显低于对照组(48.57%),差异有统计学意义(P＜0.05),两组心律失常、凝血异常及皮肤冻伤间发生率无明显差异,但仪器组寒战发生率仅为2.86%,明显低于对照组的22.86%,差异有统计学意义(P＜0.05)。结论 新型降温装置对中枢性高热患者降温速度和降温有效率更佳,不良反应较少。
Abstract
Objective To explore the efficacy and safety of a new type of cryogenic intravenous infusion device on patients with central hyperthermia.Methods The patients with central hyperthermia hospitalized in Characteristics Medical Center of Chinese People's Armed Police Force from January to October of 2022 were divided into instrumental group (35 cases) and control group (35 cases) by the willingness of patients or the families whether to use the new cryogenic intravenous infusion device or not. The control group was given routinely intravenous infusion of 4 ℃ liquid, while the instrumental group was given intravenous infusion of 4 ℃ liquid by the cryogenic intravenous infusion device. The patient's body temperature was dynamically monitored, and the cooling was stopped when the body temperature dropped to 38 ℃. The time required for the body temperature drop to 38 ℃, the cooling efficiency and the occurrence of adverse reactions between the two groups were compared.Results The time required for the body temperature drop to 38 ℃ in the control group (6.44±0.77 h) was significantly higher than that (4.47±0.84 h) in the instrumental group (P<0.05), and the effective cooling rate of the control group (57.14%) was also significantly lower than that (82.86%) of the instrumental group (P<0.05).The occurrence of adverse reactions in the instrumental group was 22.86%, which was significantly lower than 48.57% of the instrumental group (P<0.05).There was no significant difference of the incidences of arrhythmia, coagulation abnormality and skin frostbite between two groups, but the incidence of chills in the instrumental group was only 2.86%, which was significantly lower than 22.86% in the control group (P<0.05).Conclusions The new cryogenic intravenous infusion device is characterized by faster cooling speed, better efficiency, and less adverse reactions for patients with central hyperthermia.
关键词
中枢性高热 /
低温静脉输液装置 /
物理降温 /
降温效果
Key words
central hyperthermia /
cryogenic intravenous infusion device /
physical cooling /
cooling effect
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基金
军队护理创新与培育专项计划培育项目(2021HL106)
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