目的 分析新兵入伍集训中肾脏损伤相关预警指标。方法 选取武警某部入伍新兵126名,按照训练大纲集中2个月体能训练,分别以集训开始、集训第3天、1周、2周、 1个月、2个月为6个检测时间点,检测肾功能、尿常规、尿微量蛋白等指标。结果 尿微量蛋白在集训后2周[(20.78±4.45)mg/L]、集训1个月[(21.62±5.66)mg/L]、集训2个月[(21.62±5.66)mg/L]显著升高,血清肌酐(Cr)、血清尿素氮(BUN)变化幅度在生理值范围内,均与集训前对比差异有统计学意义(P＜0.05)。集训期间尿红细胞计数差异无统计学意义。肌红蛋白一过性增高至(138.11±14.07)g/L后恢复近正常水平[(25.20±11.12)g/L],新兵集训1 km跑成绩为(226.2±19.3)s,较新训前明显提高,差异有统计学意义(P＜0.05)。结论 集训方案未对肾脏造成损伤,尿微量蛋白作为敏感性更强的指标可有效提示训练后肾早期损伤。
Abstract
Objective To evaluate the early warning indexes related with renal function impairment in recruit training.Methods A total of 126 recruits of mobile forces were selected as research targets. According to the training program, they concentrated on physical training for 2 months and carried out follow-up regular inspection. The 6 test time points were the beginning of the training, 3 days of training, 1 week, 2 weeks, 1 month and 2 months of training. After getting up, the renal function, urine routine test, urine micro protein and other indexes were measured.Results Urinary microprotein significantly increased after 2 weeks [(20.78±4.45) mg/L], 1 month [(21.62±5.66) mg/L] and 2 months [(21.62±5.66) mg/L], and the changes of serum creatinine (Cr) and serum urea nitrogen (BUN) were within the range of physiological values. There was statistical significance compared with before training (P<0.05). There was no significant difference in urine red blood cell count during training. After transient increase to (138.11±14.07) g/L, myoglobin recovered to nearly normal level [(25.20±11.12) g/L], and the 1 km running performance of recruits was (226.2±19.3) s, which was significantly higher than that before the new training, and the difference was statistically significant (P<0.05).Conclusions The intensive recruit training program does not cause damage to kidney, and as a more sensitive indicator, urinary microprotein can effectively indicate the early renal function impairment after training.
关键词
军事集训 /
肾功能损伤 /
尿微量蛋白 /
血清肌酐 /
尿常规
Key words
military training /
renal function impairment /
urine microprotein /
serum creatinine /
urinalysis
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