目的 比较乙状结肠癌患者采用腹腔镜下手术与开腹手术的治疗效果。方法 选取2016-06至2023-06在武警特色医学中心特勤急救外科行手术治疗的50例乙状结肠癌患者为研究对象,按采用手术方法不同分为观察组及对照组,每组25例。对照组采用传统开腹手术治疗,观察组采用腹腔镜手术治疗。对两组患者术后并发症的发生率、炎症因子水平、白细胞及中性粒细胞水平进行对比分析。结果 观察组平均手术时间明显长于对照组,但差异无统计学意义。对照组术后切口感染率为16.0%(4/25),明显高于观察组(0/25),差异有统计学意义(P<0.05);观察组与对照组比较,术中出血量明显减少,术后肠鸣音的恢复时间及总住院时间也明显缩短,差异有统计学意义(P<0.05)。观察组术后并发症发生率和 TNF-α、IL-6、IL-1β、WBC、ANC的水平均明显低于对照组,差异有统计学意义(P<0.05)。结论 腹腔镜手术治疗乙状结肠癌效果显著,术中出血量少,可降低并发症的发生,缩短肠鸣音恢复时间,减少术后住院时间,减轻促炎因子的水平。
Abstract
Objective To compare the efficacy of laparoscopic surgery and open surgery for patients with sigmoid colon cancer. Methods A total of 50 patients with sigmoid colon cancer who underwent emergency surgery in the Characteristics Medical Center of Chinese People's Armed Police Force from June 2016 to June 2023 were selected and divided into an observation group and a control group according to the random number table method, with 25 patients in each group. The control group was treated with traditional open surgery, and the observation group was treated with laparoscopic surgery. The incidence of postoperative complications, levels of inflammatory factors, leukocytes and neutrophils were compared between the two groups. Results The average operation time of the observation group was significantly longer than that of the control group, but there was no statistical significance. The incidence of postoperative incision infection complications in the observation group was 0% (0/25), which was significantly lower than 16.0% (4/25) in the control group, and the difference was statistically significant (P<0.05); The intraoperative blood loss, postoperative bowel sound recovery time and hospital stay of the observation group were lower than those of the control group, the incidence of postoperative complications and the levels of TNF-α, IL-6, IL-1β, WBC and ANC were significantly lower than those of the control group, the differences were statistically significant (P<0.05). Conclusions Laparoscopic surgery is effective in the treatment of sigmoid colon cancer, with less intraoperative blood loss, which can reduce the occurrence of complications, shorten the recovery time of bowel sounds, reduce the length of hospital stay, and reduce the level of pro-inflammatory factors.
关键词
乙状结肠癌 /
腹腔镜手术 /
炎性因子水平 /
并发症 /
开腹手术
Key words
sigmoid carcinoma /
laparoscopic surgery /
inflammatory factor level /
complication /
open surgery
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