缺氧诱导的肠道损伤与肠易激综合征的可能关系

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武警医学 ›› 2024, Vol. 35 ›› Issue (3) : 243-247.

综述

缺氧诱导的肠道损伤与肠易激综合征的可能关系

李灵剑^1,2, 张兴光², 刘铭君^1,2, 丁杨娟^1,2, 范慧娟^1,2, 夏时海²

作者信息 +

Possible relationship between hypoxia-induced intestinal injury and irritable bowel syndrome

LI Lingjian, ZHANG Xingguang, LIU Mingjun, et al

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摘要

目前肠易激综合征(IBS)发病机制仍没有完全清楚,大量研究表明,肠道屏障功能受损可能是最主要的原因,可能与肠道紧密连接的破坏、神经调节紊乱及肠道微生物群失调等有关。高原地区IBS的患病率相对于平原有所增高,这可能与缺氧导致肠道屏障损伤有关,但目前关于缺氧与IBS关系的研究极少,因此,笔者从缺氧、肠道屏障与IBS之间的关系进行文献复习,为IBS的预防和治疗提供依据。

关键词

缺氧 / 肠道屏障 / 肠易激综合征

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李灵剑, 张兴光, 刘铭君, 丁杨娟, 范慧娟, 夏时海. 缺氧诱导的肠道损伤与肠易激综合征的可能关系[J]. 武警医学. 2024, 35(3): 243-247

LI Lingjian, ZHANG Xingguang, LIU Mingjun, et al. Possible relationship between hypoxia-induced intestinal injury and irritable bowel syndrome[J]. Medical Journal of the Chinese People Armed Police Forces. 2024, 35(3): 243-247

中图分类号： R574.4

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