高龄社区获得性肺炎患者临床危险因素分析

PDF(951 KB)

武警医学 ›› 2024, Vol. 35 ›› Issue (4) : 349-352.

综述

高龄社区获得性肺炎患者临床危险因素分析

祁琳¹, 来纯云¹, 张海洋², 赵雪桐³, 王南方³, 王玉玲⁴

作者信息 +

Analysis of clinical risk factors in elderly patients with community-acquired pneumonia

QI Lin, LAI Chunyun, ZHANG Haiyang, et al

Author information +

文章历史 +

摘要

对国内外高龄社区获得性肺炎(CAP)患者易感性生理机制、不典型临床表现和复杂的病原学特征进行综述,分析高龄CAP患者临床危险性来源,并归纳临床危险性评价指标,旨在帮助临床早期识别获得性肺炎并进行干预治疗。

关键词

高龄 / 社区获得性肺炎 / 下呼吸道感染 / 危险因素 / 临床特征

引用本文

EndNote

Ris (Procite)

Bibtex

导出引用

祁琳, 来纯云, 张海洋, 赵雪桐, 王南方, 王玉玲. 高龄社区获得性肺炎患者临床危险因素分析[J]. 武警医学. 2024, 35(4): 349-352

QI Lin, LAI Chunyun, ZHANG Haiyang, et al. Analysis of clinical risk factors in elderly patients with community-acquired pneumonia[J]. Medical Journal of the Chinese People Armed Police Forces. 2024, 35(4): 349-352

中图分类号： R563.2

参考文献

[1] 李萌博,姚佳春,王晓莉. 清肺消炎丸联合左氧氟沙星治疗官兵CAP42例[J].武警医学, 2023, 34(6):524-526.
[2] Cillóniz C, Liapikou A, Martin L I, et al. Twenty-year trend in mortality among hospitalized patients with pneumococcal community-acquired pneumonia[J]. PloS One, 2018, 13(7): e0200504.
[3] 安娜.《2022年度国家老龄事业发展公报》发布[J]. 社会与公益, 2023(12):7.
[4] Laporte L, Hermetet C, Jouan Y, et al. Ten-year trends in intensive care admissions for respiratory infections in the elderly[J]. Ann Intensive Care, 2018, 8(1): 84.
[5] Mahendra M, Jayaraj B S, Limaye S, et al. Factors influencing severity of community-acquired pneumonia[J]. Lung India, 2018, 35(4):284-289.
[6] Nguyen D T, Huynh S T, Nguyen H N. Short-term readmission following community-acquired pneumonia: a cross-sectional study[J]. Hosp Pharm, 2022, 57(6):712-720.
[7] Zhao L H, Chen J, Zhu R X. The relationship between frailty and community-acquired pneumonia in older patients[J]. Aging Clin Exp Res, 2023, 35(2):349-355.
[8] Furman, Christian D,Leinenbach, A, et al. Pneumonia in older adults[J]. Curr Opin Infect Dis, 2021, 34(2):135-141.
[9] Metlay J P, Waterer G W, Long A C, et al. Diagnosis and treatment of adults with community-acquired pneumonia. an official clinical practice guideline of the american thoracic society and infectious diseases society of america[J]. Am J Respir Crit Care Med, 2019, 200(7): e45-e67.
[10] Cillóniz C, Dominedò C, Pericàs J M, et al. Community-acquired pneumonia in critically ill very old patients: a growing problem[J]. Eur Respir Rev, 2020, 29(155):190126.
[11] Cho S J, Stout H W. Aging and lung disease[J]. Annu Rev Physiol, 2020, 82:433-459.
[12] He M, Borlak J. A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence[J]. Immun Ageing, 2023, 20(1):58.
[13] Makino K, Shimizu R, Goda N, et al. Unbiased, comprehensive analysis of Japanese health checkup data reveals a protective effect of light to moderate alcohol consumption on lung function. Sci Rep, 2021, 11(1):15954.
[14] Hamazaki N, Masuda T, Kamiya K, et al. Respiratory muscle weakness increases dead-space ventilation ratio aggravating ventilation-perfusion mismatch during exercise in patients with chronic heart failure[J]. Respirology, 2019, 24(2):154-161.5
[15] Chebib N, Cuvelier C, Malézieux P A, et al. Pneumonia prevention in the elderly patients: the other sides[J]. Aging Clin Exp Res, 2021, 33(4):1091-1100.
[16] Chen Y, Klein S L, Garibaldi B T, et al. Aging in COVID-19: vulnerability, immunity and intervention[J]. Ageing Res Rev, 2021, 65:101205.
[17] Guo R N, Dan Z, Fan Z, et al. Clinical characteristics and pathogen analysis of bronchoalveolar lavage fluid in elderly patients with community-acquired pneumonia[J]. Immun Inflamm Dis, 2023, 11(4):e813.
[18] Song Y, Wang X, Lang K, et al. Development and validation of a nomogram for predicting 28-day mortality on admission in elderly patients with severe community-acquired pneumonia[J]. J Inflamm Res, 2022, 15:4149-4158.
[19] Ryoo N, Pyun J M, Baek M J, et al. Coping with dementia in the middle of the COVID-19 pandemic[J]. J Korean Med Sci, 2020, 35(42): e383.
[20] Schöll N, Rohde G U. Ambulant erworbene pneumonie beiälteren menschen community-acquired pneumonia in the elderly[J]. Pneumologie, 2019, 73(10):605-616.
[21] Li Z J, Zhang H Y, Ren L L, et al. Etiological and epidemiological features of acute respiratory infections in China[J]. Nat Commun, 2021, 12(1): 5026.
[22] Lansbury L, Lim B, Baskaran V, et al. Co-infections in people with COVID-19: a systematic review and meta-analysis[J]. J Infect, 2020, 81(2):266-275.
[23] Han X, Zhou F, Li H, et al. Effects of age, comorbidity and adherence to current antimicrobial guidelines on mortality in hospitalized elderly patients with community-acquired pneumonia[J].BMC Infect Dis, 2018, 18(1): 192.
[24] Lin W H, Chiu H C, Chen K F, et al. Molecular detection of respiratory pathogens in community-acquired pneumonia involving adults[J]. J Microbiol Immunol Infect, 2022, 55(5): 829-837.
[25] Yamasue M, Komiya K, Kinjo T, et al. Rebound mortality rate of Legionella pneumonia in Japan[J]. Respir Investig, 2023, (4):487-489.
[26] Viasus D, Gaia V, Manzur B C, et al. Legionnaires' disease: update on diagnosis and treatment[J]. Infect Dis Ther, 2022, 11(3):973-986.
[27] Liu Y N, Zhang Y F, Xu Q, et al. Chinese center for disease control and prevention etiology surveillance study team of acute respiratory infections. infection and co-infection patterns of community-acquired pneumonia in patients of different ages in China from 2009 to 2020: a national surveillance study[J]. Lancet Microbe, 2023, 4(5):e330-e339.
[28] Costa M I, Cipriano A, Santos F V, et al. Clinical profile and microbiological aetiology diagnosis in adult patients hospitalized with community-acquired pneumonia[J]. Pulmonology,2022, 28(5):358-367.
[29] Miellet W R, Veldhuizen J, Nicolaie M A, et al. Influenza-like illness exacerbates pneumococcal carriage in older adults[J]. Clin Infect Dis, 2021, 73(9):e2680-e2689.
[30] Kirtipal N, Bharadwaj S, Kang S G. From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses[J]. Infect Genet Evol, 2020, 85:104502.
[31] Tian H, Liu Y, Li Y, et al. An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China[J]. Science, 2020, 368(6491): 638-642.
[32] Chen B, Tian E K, He B, et al. Overview of lethal human coronaviruses[J]. Signal Transduct Target Ther, 2020, 5(1): 89.
[33] Lu Q B, Zhang H Y, Che T L, et al. The differential demographic pattern of coronavirus disease 2019 fatality outside Hubei and from six hospitals in Hubei, China: a descriptive analysis[J]. BMC Infect Dis, 2021, 21(1): 481.
[34] Azoilay E, Vincent J L, Angus D C, et al. Recovery after critical illness: putting the puzzle together-a consensus of 29[J]. Crit Care, 2017, 21(1): 296.
[35] Torres A, Cilloniz C, Niederman M S, et al. Pneumonia[J]. Nat Rev Dis Primers, 2021, 7(1):25.
[36] Altuna V S, Aliaga V R, Maguiña J L, et al. Risk of community-acquired pneumonia in older adults with sarcopenia of a hospital from Callao, Peru 2010-2015[J]. Arch Gerontol Geriatr, 2019, 82: 100-105.
[37] Hespanhol V, Bárbara C. Pneumonia mortality, comorbidities matter?[J].Pulmonology, 2020, 26(3):123-129.
[38] Kofteridis D P, Giourgouli G, Plataki M N, et al. Community-acquired pneumonia in elderly adults with type 2 diabetes mellitus[J]. J Am Geriatr Soc, 2016, 64(3): 649-651.
[39] Lin C J, Chang Y C, Tsou M T, et al. Factors associated with hospitalization for community-acquired pneumonia in home health care patients in Taiwan[J]. Aging Clin Exp Res, 2020, 32(1): 149-155.
[40] Yeo H J, Byun K S, Han J, et al. Prognostic significance of malnutrition for long-term mortality in community-acquired pneumonia: a propensity score matched analysis[J]. Korean J Intern Med, 2019, 34(4): 841-849.
[41] Guo Y, Ng N, Hassler S, et al. Frailty trajectories in Chinese older adults: evidence from the china health and retirement longitudinal study[J]. Innov Aging, 2023, 8(1):igad131.
[42] Zhao H, Tu J, She Q, et al. Prognostic significance of frailty in hospitalized elderly patients with community-acquired pneumonia: a retrospective cohort study[J]. BMC Geriatr, 2023, 23(1):308.
[43] Niederman M S, Cilloniz C. Aspiration pneumonia[J]. Rev Esp Quimioter, 2022, 35 Suppl 1(Suppl 1):73-77.