[1] 谭 睿. 中国老年人口失能状况及变化分析——基于第六次、第七次全国人口普查数据[J]. 卫生经济研究,2023,40(3):6-11. [2] 马丽娜. 老年衰弱综合征的发病机制[J]. 中华老年医学杂志,2021,40(3):379-382. [3] Ruan Q, Yu Z, Chen M, et al. Cognitive frailty, a novel target for the prevention of elderly dependency[J]. Ageing Res Rev, 2015,20:1-10. [4] Zheng L, Li G, Gao D, et al. Cognitive frailty as a predictor of dementia among older adults: a systematic review and meta-analysis[J]. Arch Gerontol Geriatr, 2020,87:103997. [5] 韩飒飒, 王艳梅. 老年人认知衰弱评估及危险因素研究进展[J]. 护理研究,2021,35(7):1199-1202. [6] 王丽文. 老年共病住院患者认知衰弱的影响因素分析[D].唐山:华北理工大学,2021. [7] 李 扬, 赵 梦, 陈 欧,等. 社区老年人认知衰弱发生率的Meta分析[J]. 齐鲁护理杂志,2023,29(15): 55-61. [8] Ge M L, Simonsick E M, Dong B R, et al. Frailty, with or without cognitive impairment, is a strong predictor of recurrent falls in a US population-representative sample of older adults [J]. J Gerontol A Biol Sci Med Sci, 2021, 76(11): e354-e360. [9] Vargas-Torres-Young D A, Salazar-Talla L, Cuba-Ruiz S, et al. Cognitive frailty as a predictor of mortality in older adults: a longitudinal study in Peru[J]. Front Med (Lausanne), 2022, 9: 910005. [10] 杜 瑾, 宋安妮, 张伟宏. 老年人认知衰弱及其干预策略的研究进展[J]. 中华现代护理杂志,2021,27(33):4499-4504. [11] Katayama O, Lee S, Bae S, et al. Lifestyle activity patterns related to physical frailty and cognitive impairment in urban community-dwelling older adults in Japan[J]. J Am Med Dir Assoc, 2021,22(3):583-589. [12] Chen X, Zhao L, Liu Y, et al. Otago exercise programme for physical function and mental health among older adults with cognitive frailty during COVID-19: a randomised controlled trial[J]. J Clin Nurs, 2021, 10:15964. [13] Merchant R A, Chan Y H, Hui R, et al. Motoric cognitive risk syndrome, physio-cognitive decline syndrome, cognitive frailty and reversibility with dual-task exercise[J]. Exp Gerontol, 2021, 150: 111362. [14] 公维军, 张玉梅. 认知衰弱康复中国专家共识2023[J]. 中国医刊,2023,58(9):949-953. [15] Picca A, Calvani R, Cesari M, et al. Biomarkers of physical frailty and sarcopenia: coming up to the place?[J]. Int J Mol Sci, 2020, 21(16):5635. [16] Karamacoska D, Butt A, Leung I, et al. Brain function effects of exercise interventions for cognitive decline: a systematic review and meta-analysis [J]. Front Neurosci, 2023, 17: 1127065. [17] Wang Z, Wang J, Guo J, et al. Association of motor function with cognitive trajectories and structural brain differences: a community-based cohort study [J]. Neurology, 2023, 101(17):e1718-e1728. [18] El Assar M, Angulo J, Rodríguez-Maías L. Frailty as a phenotypic manifestation of underlying oxidative stress[J]. Free Radic Biol Med, 2020, 149: 72-77. [19] Knezevic D, Mizrahi R. Molecular imaging of neuroinflammation in Alzheimer's disease and mild cognitive impairment[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2018, 80(Pt B):123-131. [20] 徐率轩, Huang wei, 孔二艳,等. 氧化应激在衰弱发病机制中的作用[J]. 中华老年多器官疾病杂志,2022,21(11):858-862. [21] 母 蕾, 巫嘉陵. 衰弱与炎症[J]. 中国现代神经疾病杂志,2020, 20(1):61-64. [22] Lee B K, Glass T A, McAtee M J, et al. Associations of salivary cortisol with cognitive function in the Baltimore memory study [J]. Arch Gen Psychiatry, 2007, 64(7): 810-818. [23] Cheetham N J, Penfold R, Giunchiglia V, et al. The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study [J]. E Clinical Medicine, 2023, 62: 102086. [24] Stein S R, Ramelli S C, Grazioli A, et al. SARS-CoV-2 infection and persistence in the human body and brain at autopsy [J]. Nature, 2022, 612(7941): 758-763. [25] Stilling R M, Dinan T G, Cryan J F. Microbial genes, brain & behaviour-epigenetic regulation of the gut-brain axis[J]. Genes Brain Behav, 2014, 13(1): 69-86. [26] Schroeder B O, Bäckhed F. Signals from the gut microbiota to distant organs in physiology and disease [J]. Nat Med, 2016, 22(10): 1079-1089. [27] Bajaj J S, Ridlon J M, Hylemon P B, et al. Linkage of gut microbiome with cognition in hepatic encephalopathy[J]. Am J Physiol Gastrointest Liver Physiol, 2012, 302(1): G168-175. [28] Sun Y, Baptista L C, Roberts L M, et al. The gut microbiome as a therapeutic target for cognitive impairment [J]. J Gerontol A Biol Sci Med Sci, 2020, 75(7): 1242-1250. [29] Dent E, Morley J E, Cruz-Jentoft A J, et al. Physical Frailty: ICFSR international clinical practice guidelines for identification and management[J]. J Nutr Health Aging, 2019, 23(9): 771-787. [30] Tsugawa A, Shimizu S, Hirose D, et al. Effects of 12-month exercise intervention on physical and cognitive functions of nursing home residents requiring long-term care: a non-randomised pilot study [J]. Psychogeriatrics, 2020, 20(4): 419-426. [31] 叶 明, 李书国, 朱正庭,等. 多组分运动处方对认知衰弱老年人的影响研究[J]. 中国全科医学,2021,24(4):460-466. [32] 陈艳林, 徐 琳, 徐盛嘉. 身体活动对海马体可塑性和认知功能的影响[J]. 中国组织工程研究,2020,24(5):773-779. [33] Voet N B, van der Kooi EL, van Engelen B G, et al. Strength training and aerobic exercise training for muscle disease [J]. Cochrane Database Syst Rev, 2019, 12(12): CD003907. [34] 李墨逸. 基于默认网络的八段锦运动干预轻度认知障碍的功能影像学研究[D]. 福州:福建中医药大学,2017. [35] Tao J, Chen X, Egorova N, et al. Tai Chi Chuan and Baduanjin practice modulates functional connectivity of the cognitive control network in older adults [J]. Sci Rep, 2017, 7: 41581. [36] 叶 钰. 八段锦对认知衰弱老年人氧化应激和慢性炎症的影响研究[D].福州:福建中医药大学,2022. [37] 周 园, 张 婧, 陈建刚,等. 抗阻训练在骨骼肌减少症中应用效果的Meta分析[J]. 护理研究, 2021, 35(22): 3960-3967. [38] Yoon D H, Lee J Y, Song W. Effects of resistance exercise training on cognitive function and physical performance in cognitive frailty: a randomized controlled trial[J]. J Nutr Health Aging, 2018, 22(8): 944-951. [39] Coelho-Júnior H J, Uchida M C. Effects of low-speed and high-speed resistance training programs on frailty status, physical performance, cognitive function, and blood pressure in prefrail and frail older adults [J]. Front Med (Lausanne), 2021, 8: 702436. [40] 胡娇娇. 弹力带抗阻训练联合八段锦对COPD患者体力活动及生存质量的影响[D]. 南昌: 南昌大学,2023. [41] Strasser E M, Hofmann M, Franzke B, et al. Strength training increases skeletal muscle quality but not muscle mass in old institutionalized adults: a randomized, multi-arm parallel and controlled intervention study [J]. Eur J Phys Rehabil Med, 2018, 54(6): 921-933. [42] 韩 君, 王君俏, 高 键,等. 弹力带运动联合认知训练对社区老年人认知衰弱的干预效果[J]. 护理研究, 2022,36(4): 624-629. [43] Almarzouki R, Bains G, Lohman E, et al. Improved balance in middle-aged adults after 8 weeks of a modified version of Otago Exercise Program: A randomized controlled trial[J]. PLoS One, 2020,15(7):e0235734. [44] 裴鑫悦, 卢孟倩, 汪凤兰,等. 奥塔戈运动训练对老年人跌倒恐惧的影响[J]. 护理研究,2023,37(19):3555-3557. [45] 秦 琴, 田丹英. 认知-奥塔戈运动控制双重任务训练对改善动脉瘤性蛛网膜下腔出血病人认知功能及肢体运动功能的影响[J]. 循证护理, 2023, 9(2): 333-337. [46] 罗宝林, 罗泽槟, 陈森芸,等. 老年人衰弱预防与延迟或逆转干预的证据总结[J]. 护理学杂志,2021,36(14):32-37. [47] Morishita S, Tsubaki A, Nakamura M, et al. Rating of perceived exertion on resistance training in elderly subjects [J]. Expert Rev Cardiovasc Ther, 2019, 17(2): 135-142. [48] Nelson M E, Rejeski W J, Blair S N, et al. Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association[J]. Circulation, 2007, 116(9): 1094-1105. [49] 赖小星, 刘 薇, 朱宏伟,等. 抗阻训练对衰弱老年人肌力和体适能的剂量效应关系研究[J]. 北京医学,2022,44(12):1063-1069,1074. [50] 乔晓霞, 季丽丽, 司华新,等. 社区衰弱老年人运动干预研究进展[J]. 中国老年学杂志, 2020, 40(15):3346-3350. [51] 中国老年护理联盟, 中南大学湘雅护理学院(中南大学湘雅泛海健康管理研究院), 中南大学湘雅医院(国家老年疾病临床医学研究中心),等. 认知衰退老年人非药物干预临床实践指南:身体活动[J]. 中国全科医学, 2023, 26(16):1927-1937, 1971.