目的 探讨药师在规范普外科预防性使用抗菌药物中的作用。方法 回顾性分析2021-01至2023-12武警江西总队医院普外科收治的136例Ⅰ、Ⅱ类切口手术患者的临床资料。根据药师是否干预普外科医师预防性使用抗菌药物,分为干预组(74例)和对照组(62例)。比较两组患者在预防性抗菌药物使用率、用药时长、用药品种、给药时间、联合用药以及预防用药合理率方面的差异。结果 两组患者基本情况的比较,差异无统计学意义(P＞0.05),具有可比性。干预组预防性抗菌药物使用率为32.43%,对照组为88.71%;干预组联合用药比例为4.05%,对照组为20.97%;干预组预防用药合理率为72.97%,对照组为17.74%,差异有统计学意义(P＜0.05)。干预组预防性使用抗菌药物的用药时长、用药品种和给药时间的合理率均优于对照组。结论 临床药师协作,可以有效规范普外科预防性使用抗菌药物。
Abstract
Objective To explore the important role of pharmacists in standardizing the prophylactic antimicrobial applications in general surgery. Methods The clinical data of 136 patients undergoing Class I and II incision surgery admitted to the General Surgery Department of Jiangxi Armed Police Corps Hospital from January 2021 to December 2023 were retrospectively analyzed. Based on the pharmacist’s intervention in the prophylactic use of antimicrobials, the patients were divided into an intervention group (74 cases) and a control group (62 cases).Compare the differences between the two groups of patients in terms of the prophylactic antimicrobial use rate, the medication duration, the medication type, the administration time, the combination of medications, and the reasonable rate of prophylactic medication. Results Comparison of the basic conditions of the patients in the two groups showed no statistically significant differences (P>0.05), and the data were comparable. The prophylactic antimicrobial usage rate in the intervention group was 32.43%, compared to 88.71% in the control group; the rate of combined medication use was 4.05% in the intervention group and 20.97% in the control group; the rationality rate of prophylactic medication use was 72.97% in the intervention group and 17.74% in the control group, with statistically significant differences (P＜0.05). The intervention group demonstrated superior rationality in the duration, selection, and timing of prophylactic antimicrobial use compared to the control group. Conclusion Pharmacists play an important role in standardizing the prophylactic antimicrobial applications in general surgery, and the intervention measures demonstrating a positive impact.
关键词
干预 /
抗菌药物 /
围手术期
Key words
intervention /
antibiotics /
perioperative period
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