脑深部电刺激术治疗帕金森病的临床研究进展

丁瑞文, 杨海军, 王亚涛, 马行远, 邓庭桢, 张宇航, 李浩天, 王大文, 孙洪涛, 郑茂华

武警医学 ›› 2025, Vol. 36 ›› Issue (4) : 349-352.

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武警医学 ›› 2025, Vol. 36 ›› Issue (4) : 349-352.
综述

脑深部电刺激术治疗帕金森病的临床研究进展

  • 丁瑞文1, 杨海军1, 王亚涛1, 马行远1, 邓庭桢1, 张宇航1, 李浩天1, 王大文1, 孙洪涛2, 郑茂华1
作者信息 +
文章历史 +

摘要

脑深部电刺激术(DBS)作为一种个体化的可逆神经调控手段,近年来在帕金森病治疗领域取得了显著进展,其通过刺激特定的脑区,如丘脑底核和苍白球内侧部,改善患者的运动与非运动症状,同时减少药物相关的并发症。随着DBS治疗机制研究的不断深入,研究者通过探索神经网络活动的调控模式,为帕金森病的治疗提供了新视角。本文总结DBS在帕金森病治疗中的最新进展,包括手术靶点的选择、手术时机的评估以及潜在机制的探讨,并展望其未来发展方向,为进一步研究和临床应用提供参考。

关键词

帕金森病 / 外科治疗 / 脑深部电刺激术

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丁瑞文, 杨海军, 王亚涛, 马行远, 邓庭桢, 张宇航, 李浩天, 王大文, 孙洪涛, 郑茂华. 脑深部电刺激术治疗帕金森病的临床研究进展[J]. 武警医学. 2025, 36(4): 349-352
中图分类号: R742.5   

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基金

神经外科硕士学位点规范化建设项目(lzuyxcx-2022-132);椎基底动脉扩张延长症相关颅神经疾病的临床研究(2022-ZD-93);Has-circ-0101145调控脑胶质瘤增值、侵袭和EMT作用机制研究(21JR7RA356)

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