目的 探讨不同强度静态负荷对健康人群眼压及血压的影响。方法 从健康人群中随机选取45名作为受试对象。在站立状态下测量眼压平均值及血压值,测量双手抱持2.5、5.0、7.5、10.0、12.5、15.0、17.5、20.0 kg等重物时的眼压平均值及血压值,在解除负荷10、20、30、60 min时再次测量眼压平均值,将未负荷状态下的眼压值、血压值作为基线数值,检测不同强度负荷状态下的眼压值、血压值及解除负荷后不同时间眼压值作为实验组数值。结果 不同负荷强度的平均眼压与无负荷（0 kg）相比,各负荷强度眼压水平均高于无负荷（0 kg）,差异均有统计学意义（P0.05）,但2.5 kg负荷时,眼压虽高于无负荷（0 kg）,但差异无统计学意义。与未负荷状态相比,不同负荷强度血压水平总体上差异有统计学意义（P0.001）,且血压均高于基线水平。在解除负荷10、20、30 min下,平均眼压相比基线数值差异有统计学意义（P0.05),解除负荷60 min后,平均眼压与基线数值差异无统计学意义（P0.05）。结论 在不同强度静态负荷条件下,受试者平均眼压和血压水平出现短暂上升趋势,解除负荷后眼压逐渐趋于稳定。
Abstract
Objective To explore the effects of static loads of different intensities on intraocular pressure (IOP) and blood pressure (BP) in healthy individuals. Methods Forty-five healthy individuals were randomly selected from the healthy population as study subjects. The average IOP and BP were measured in a standing position. The average IOP and BP were measured when the subjects held weights of 2.5, 5.0, 7.5, 10.0, 12.5, 15.0, 17.5, and 20.0 kg with both hands. The average IOP and BP were remeasured at 10, 20, 30, and 60 minutes after the load was removed. The IOP and BP values under the unloaded state served as baseline reference values. The values of IOP and BP under different intensity load conditions and the IOP values at various time points after load removal were detected as the experimental group values. Results The average IOP under varying load intensities was significantly elevated compared with the unloaded condition, and the differences were statistically significant (P<0.05). However, no statistically significant difference in IOP was detected between the 2.5 kg load condition and other loaded conditions. In contrast, the average BP under various load intensities showed statistically significant differences compared with the no-load condition (P<0.001), with blood pressure being consistently higher than baseline values. After unloading, the average IOP at 10, 20, and 30 minutes exhibited significant differences compared with baseline values (P<0.05). At 60 minutes of load relief, there was no statistically significant difference in the average IOP compared with the baseline values. (P > 0.05). Conclusions Under different static load intensity conditions, both IOP and BP levels demonstrate a transient upward trend, with IOP gradually stabilizing after the load was relieved.
关键词
静态负荷 /
眼压 /
收缩压 /
舒张压
Key words
static load /
intraocular pressure /
systolic blood pressure /
diastolic blood pressure
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基金
首都卫生发展科研专项 （2022-2-5041）
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