目的 系统评价运动锻炼方式及时间对减轻维持性血液透析（MHD）患者疲乏的效果。方法 通过计算机检索医学文献数据库自建库以来至2022年1月发表的有关运动训练干预MHD患者疲乏的临床研究,并提取相关资料和评估质量后,使用RevMan5.4软件加以分析。结果 共纳入12篇文献,包括1064例患者。运动锻炼对改善MHD患者的疲乏效果明显（MD=-2.60,95%CI：-2.83~-2.38,P0.01）,在运动参数方面,纳入的研究中,干预频次均为每周3~5次。有氧联合抗阻运动,运动时间≥12周,每次运动30~40 min在干预MHD患者疲乏方面取得较好疗效。结论 运动锻炼有利于帮助MHD患者减轻疲乏。
Abstract
Objective To systematically evaluate the effect of exercise method and time on alleviating fatigue in patients with maintenance hemodialysis（MHD）. Methods Computerized searches were conducted in medical literature databases from their establishment until January 2022 to identify clinical studies on exercise training intervention for MHD patients’ fatigue. Relevant data were extracted and the quality was assessed, and then analyzed using RevMan5.4 software. Results A total of 12 studies were included, involving 1064 patients. Exercise significantly improved the fatigue of MHD patients(MD=-2. 60, 95%CI:-2. 83 to 2.38, P < 0.00001). In terms of exercise parameters, the intervention frequency was 3 to 5 times per week in all the included studies. Aerobic combined with resistance exercise, exercise time ≥12 weeks and each session lasting 30 to 40 minutes achieved better therapeutic effects in alleviating the fatigue of MHD patients. Conclusions Exercise is beneficial for helping MHD patients alleviate fatigue.
关键词
运动锻炼 /
维持性血液透析 /
疲乏 /
Meta分析
Key words
exercise /
maintenance hemodialysis /
fatigue /
Meta analysis
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