肠道菌群在肝脏疾病发生发展中的作用研究进展

章保新, 龚家辉, 简明, 袁桔华, 张祖萍

武警医学 ›› 2026, Vol. 37 ›› Issue (1) : 75-81.

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武警医学 ›› 2026, Vol. 37 ›› Issue (1) : 75-81.
综述

肠道菌群在肝脏疾病发生发展中的作用研究进展

  • 章保新1, 龚家辉1, 简明1, 袁桔华1, 张祖萍2
作者信息 +
文章历史 +

摘要

肠道菌群通过肠-肝轴调控机制参与多种肝脏疾病的发生发展。菌群失调导致内毒素、短链脂肪酸等代谢产物异常,破坏肠道屏障功能,激活机体免疫反应,加剧肝细胞脂肪变性、炎症及纤维化进程,与肝脏疾病的病理进展密切相关。本文阐述了肠道菌群在肝脏疾病发展中的作用机制,为将来靶向调控肠道菌群防治肝脏疾病提供新策略。

关键词

肠道菌群 / 肝脏疾病 / 肠-肝轴 / 发病机制

引用本文

导出引用
章保新, 龚家辉, 简明, 袁桔华, 张祖萍. 肠道菌群在肝脏疾病发生发展中的作用研究进展[J]. 武警医学. 2026, 37(1): 75-81
中图分类号: R575.01   

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